A biofluid-repellent nanograss coating enhances flow of protein solutions and preserves transparency of glass capillaries upon exposure to blood

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

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en

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13

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Nanoscale Advances, Volume 8, issue 1, pp. 67-79

Abstract

A transparent and superhydrophobic (SHB) nanograss coating makes glass capillaries repellent toward protein solutions and blood. The coating is fabricated using atomic layer deposited alumina which is converted into grass-like alumina (GLA) by hot water treatment (HWT). The resulting tubes are transparent and highly repellent towards water and protein solutions (sliding angle <6° for a concentrated albumin solution). The biofluid repellence of the coating reduces hydraulic resistances for protein-rich biofluids, including fetal bovine serum, by 0–50% with the strongest effect for the smallest tubes and lowest Reynolds numbers. This work addresses a knowledge gap where previous studies have mostly focused on pure water for the drag reduction effect. The tubes also show a promising ability to stay clean and transparent on short term exposure to blood, unlike unmodified glass or polymer controls.

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Hussain, M, Awashra, M, Kauppinen, C, Mirmohammadi, S M, Addy-Tayie, N, Peltola, R, Leskinen, J, Puustinen, S, Nurmi, H A, Ras, R H A, Franssila, S & Jokinen, V 2026, 'A biofluid-repellent nanograss coating enhances flow of protein solutions and preserves transparency of glass capillaries upon exposure to blood', Nanoscale Advances, vol. 8, no. 1, pp. 67-79. https://doi.org/10.1039/d5na00433k