Effect of serum dilution fluids on the wear of unirradiated and high dose gamma-irradiated, vitamin E stabilized UHMWPE

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Journal Title
Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Date
2019-07-15
Major/Subject
Mcode
Degree programme
Language
en
Pages
5
76-80
Series
Wear, Volume 430-431
Abstract
In orthopaedic tribology, the ISO 14242-1 standard recommends that the serum lubricant is diluted with deionized water (DW). Sometimes, phosphate buffered saline (PBS) is used instead for the dilution. Noncyclic, multidirectional pin-on-disk tests showed that the dilution of alpha calf serum with PBS or phosphate buffer resulted in a 5–40-fold decrease in the wear factor of unirradiated and of vitamin E stabilized, highly crosslinked ultrahigh molecular weight polyethylene (UHMWPE) compared with DW dilution. It appears that the phosphates were mainly responsible for this phenomenon. PBS dilution may result in a substantial underestimation of clinical wear. With 1:1 DW dilution, the mean wear factor of highly crosslinked UHMWPE was 5.7-fold lower than that of unirradiated UHMWPE.
Description
Keywords
Biomedical devices, Lubrication environment, Noncyclic pin-on-disk, UHMWPE
Other note
Citation
Saikko , V 2019 , ' Effect of serum dilution fluids on the wear of unirradiated and high dose gamma-irradiated, vitamin E stabilized UHMWPE ' , Wear , vol. 430-431 , pp. 76-80 . https://doi.org/10.1016/j.wear.2019.04.022