Solid-State Synthesis of Cationic Cellulose Fibers from Low-Processed Cotton for Efficient Virus Capture
Loading...
Access rights
openAccess
CC BY
CC BY
publishedVersion
URL
Journal Title
Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
This publication is imported from Aalto University research portal.
View publication in the Research portal (opens in new window)
View/Open full text file from the Research portal (opens in new window)
View publication in the Research portal (opens in new window)
View/Open full text file from the Research portal (opens in new window)
Unless otherwise stated, all rights belong to the author. You may download, display and print this publication for Your own personal use. Commercial use is prohibited.
Date
Major/Subject
Mcode
Degree programme
Language
en
Pages
9
Series
ACS Sustainable Chemistry and Engineering, Volume 13, issue 42, pp. 18223-18231
Abstract
Cellulose is a plentiful natural resource that, through sustainable modification methods, provides a valuable source of innovative functional biomaterials. Positively charged cellulose can aggregate and immobilize pathogens, offering a crucial feature for biotechnological and healthcare applications. Herein, we present a solid-state synthetic approach that combines mechanochemistry and aging for the efficient cationization of low-processed cotton fibers with (2,3-epoxypropyl) trimethylammonium chloride (EPTMAC). The developed protocol eliminates solvents and water from the synthesis and significantly reduces the amount of EPTMAC required while maintaining high cationization efficiency, thus contrasting with conventional solvent- and water-intensive cellulose cationization methods. This approach allows us to substantially increase reaction mass efficiency (RME = 87%) and reduce process mass intensity (PMI = 1.5, a 12-fold decrease) in cellulose fiber cationization. The produced cationic cellulose demonstrated strong electrostatic binding with the cowpea chlorotic mottle virus (CCMV), a commonly used model system for pathogens. Consequently, filter stacks were designed, showing that the presence of just 1 wt % of the cationic fibers in a cellulose matrix suffices to remove CCMV from solution. Overall, the developed solid-state protocol enables a more efficient and sustainable methodology, reducing waste generation without compromising the applicability of cationic cellulose in areas such as biotechnology and water purification processes.Description
Publisher Copyright: © 2025 The Authors. Published by American Chemical Society
Other note
Citation
Nikonovich, T, Yu, Y, Korkiakoski, M, Yang, C, Seitz, I, Langerreiter, D, Kostiainen, M A, Anaya-Plaza, E & Kaabel, S 2025, 'Solid-State Synthesis of Cationic Cellulose Fibers from Low-Processed Cotton for Efficient Virus Capture', ACS Sustainable Chemistry and Engineering, vol. 13, no. 42, pp. 18223-18231. https://doi.org/10.1021/acssuschemeng.5c07884