Polymer translocation through a nanopore assisted by an environment of active rods
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Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date
2021-01-26
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Language
en
Pages
7
Series
PHYSICAL REVIEW RESEARCH, Volume 3, issue 1
Abstract
We use a combination of computer simulations and isoflux tension propagation (IFTP) theory to investigate the translocation dynamics of a flexible linear polymer through a nanopore into an environment composed of repulsive active rods in two dimensions. We demonstrate that the rod activity induces a crowding effect on the polymer, leading to a time-dependent effective net force that facilitates translocation into the active environment. Incorporating this force into the IFTP theory for pore-driven translocation allows us to characterize translocation dynamics in detail and derive a scaling form for the average translocation time as τ ∼ N1+v01 Lvt/FSP, where N01, Lr, and FSP are the initial contour length of the cis-side subchain, rod length, and self-propelling force acting on the rods, respectively, and ν is the equilibrium Flory scaling exponent.Description
Keywords
DNA, FORCE, TRANSITION, ROTATION, SWIMMER, MOTION
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Citation
Khalilian, H, Sarabadani, J & Ala-Nissila, T 2021, ' Polymer translocation through a nanopore assisted by an environment of active rods ', PHYSICAL REVIEW RESEARCH, vol. 3, no. 1, 013080 . https://doi.org/10.1103/PhysRevResearch.3.013080
