Similarity-based analysis of atmospheric organic compounds for machine learning applications

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

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en

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24

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Geoscientific Model Development, Volume 18, issue 9, pp. 2701-2724

Abstract

The formation of aerosol particles in the atmosphere impacts air quality and climate change, but many of the organic molecules involved remain unknown. Machine learning could aid in identifying these compounds through accelerated analysis of molecular properties and detection characteristics. However, such progress is hindered by the current lack of curated datasets for atmospheric molecules and their associated properties. To tackle this challenge, we propose a similarity analysis that connects atmospheric compounds to existing large molecular datasets used for machine learning development. We find a small overlap between atmospheric and non-atmospheric molecules using standard molecular representations in machine learning applications. The identified out-of-domain character of atmospheric compounds is related to their distinct functional groups and atomic composition. Our investigation underscores the need for collaborative efforts to gather and share more molecular-level atmospheric chemistry data. The presented similarity-based analysis can be used for future dataset curation for machine learning development in the atmospheric sciences.

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Publisher Copyright: © Author(s) 2025.

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Sandström, H & Rinke, P 2025, 'Similarity-based analysis of atmospheric organic compounds for machine learning applications', Geoscientific Model Development, vol. 18, no. 9, pp. 2701-2724. https://doi.org/10.5194/gmd-18-2701-2025