Polymer translocation in an environment of active rods

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorKhalilian, Hamidrezaen_US
dc.contributor.authorSarabadani, Jalalen_US
dc.contributor.authorAla-Nissila, Tapioen_US
dc.contributor.departmentDepartment of Applied Physicsen
dc.contributor.organizationInstitute for Research in Fundamental Sciencesen_US
dc.date.accessioned2023-08-01T06:23:42Z
dc.date.available2023-08-01T06:23:42Z
dc.date.issued2023-04en_US
dc.descriptionFunding Information: Computational resources from CSC - Center for Scientific Computing Ltd. and from the Aalto University School of Science “Science-IT” project are gratefully acknowledged. T.A-N. has been supported in part by the Academy of Finland through its PolyDyna (No. 307806) and QFT Center of Excellence Program Grants (No. 312298).
dc.description.abstractWe consider the dynamics of a translocation process of a flexible linear polymer through a nanopore into an environment of active rods in the trans side. Using Langevin dynamics simulations, we show that the rods facilitate translocation to the trans side even when there are initially more monomers on the cis than on the trans side. Structural analysis of the translocating polymer reveals that active rods induce a folded structure to the trans-side subchain in the case of successful translocation events. By keeping the initial number of monomers on the cis-side subchain fixed, we map out a state diagram for successful events as a function of the rod number density for a variety of system parameters. This reveals competition between facilitation by the rods at low densities and crowding that hinders translocation at higher densities.en
dc.description.versionPeer revieweden
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationKhalilian, H, Sarabadani, J & Ala-Nissila, T 2023, 'Polymer translocation in an environment of active rods', Physical Review Research, vol. 5, no. 2, 023107. https://doi.org/10.1103/PhysRevResearch.5.023107en
dc.identifier.doi10.1103/PhysRevResearch.5.023107en_US
dc.identifier.issn2643-1564
dc.identifier.otherPURE UUID: ea26dd63-c468-4491-bad2-8679b04b73d1en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/ea26dd63-c468-4491-bad2-8679b04b73d1en_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/116512917/Polymer_translocation_in_an_environment_of_active_rods_pdfa2b.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/122288
dc.identifier.urnURN:NBN:fi:aalto-202308014649
dc.language.isoenen
dc.publisherAmerican Physical Society
dc.relation.fundinginfoComputational resources from CSC - Center for Scientific Computing Ltd. and from the Aalto University School of Science “Science-IT” project are gratefully acknowledged. T.A-N. has been supported in part by the Academy of Finland through its PolyDyna (No. 307806) and QFT Center of Excellence Program Grants (No. 312298).
dc.relation.ispartofseriesPhysical Review Researchen
dc.relation.ispartofseriesVolume 5, issue 2en
dc.rightsopenAccessen
dc.titlePolymer translocation in an environment of active rodsen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion

Files