Albumin Stabilized Fe@C Core–Shell Nanoparticles as Candidates for Magnetic Hyperthermia Therapy

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorRamírez-Morales, Maria Antonieta
dc.contributor.authorGoldt, Anastasia E.
dc.contributor.authorKalachikova, Polina M.
dc.contributor.authorRamirez B, Javier A.
dc.contributor.authorSuzuki, Masashi
dc.contributor.authorZhigach, Alexey N.
dc.contributor.authorBen Salah, Asma
dc.contributor.authorShurygina, Liliya I.
dc.contributor.authorShandakov, Sergey D.
dc.contributor.authorZatsepin, Timofei
dc.contributor.authorKrasnikov, Dmitry V.
dc.contributor.authorMaekawa, Toru
dc.contributor.authorNikolaev, Evgeny N.
dc.contributor.authorNasibulin, Albert G.
dc.contributor.departmentSkolkovo Institute of Science and Technology
dc.contributor.departmentElectrochemical Energy Conversion
dc.contributor.departmentToyo University
dc.contributor.departmentRAS - N.N. Semenov Institute of Chemical Physics
dc.contributor.departmentKemerovo State University
dc.contributor.departmentDepartment of Chemistry and Materials Scienceen
dc.date.accessioned2022-09-21T06:07:09Z
dc.date.available2022-09-21T06:07:09Z
dc.date.issued2022-08
dc.descriptionPublisher Copyright: © 2022 by the authors.
dc.description.abstractCarbon-encapsulated iron nanoparticles (Fe@C) with a mean diameter of 15 nm have been synthesized using evaporation–condensation flow–levitation method by the direct iron-carbon gas-phase reaction at high temperatures. Further, Fe@C were stabilized with bovine serum albumin (BSA) coating, and their electromagnetic properties were evaluated to test their performance in magnetic hyperthermia therapy (MHT) through a specific absorption rate (SAR). Heat generation was observed at different Fe@C concentrations (1, 2.5, and 5 mg/mL) when applied 331 kHz and 60 kA/m of an alternating magnetic field, resulting in SAR values of 437.64, 129.36, and 50.4 W/g for each concentration, respectively. Having such high SAR values at low concentrations, obtained material is ideal for use in MHT.en
dc.description.versionPeer revieweden
dc.format.mimetypeapplication/pdf
dc.identifier.citationRamírez-Morales , M A , Goldt , A E , Kalachikova , P M , Ramirez B , J A , Suzuki , M , Zhigach , A N , Ben Salah , A , Shurygina , L I , Shandakov , S D , Zatsepin , T , Krasnikov , D V , Maekawa , T , Nikolaev , E N & Nasibulin , A G 2022 , ' Albumin Stabilized Fe@C Core–Shell Nanoparticles as Candidates for Magnetic Hyperthermia Therapy ' , Nanomaterials , vol. 12 , no. 16 , 2869 . https://doi.org/10.3390/nano12162869en
dc.identifier.doi10.3390/nano12162869
dc.identifier.issn2079-4991
dc.identifier.otherPURE UUID: e0a2e450-6f74-4ff6-8020-a82196802df6
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/e0a2e450-6f74-4ff6-8020-a82196802df6
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85137409811&partnerID=8YFLogxK
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/88348717/CHEM_Ramirez_Morales_et_al_Albumin_Stabilized_2022_Nanomaterials.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/116887
dc.identifier.urnURN:NBN:fi:aalto-202209215685
dc.language.isoenen
dc.publisherMDPI AG
dc.relation.ispartofseriesNanomaterialsen
dc.relation.ispartofseriesVolume 12, issue 16en
dc.rightsopenAccessen
dc.subject.keywordcore–shell nanoparticles
dc.subject.keywordferromagnetic particles
dc.subject.keywordflow-levitation method
dc.subject.keywordiron nanoparticles
dc.subject.keywordmagnetic hyperthermia
dc.titleAlbumin Stabilized Fe@C Core–Shell Nanoparticles as Candidates for Magnetic Hyperthermia Therapyen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
Files