Albumin Stabilized Fe@C Core–Shell Nanoparticles as Candidates for Magnetic Hyperthermia Therapy
Loading...
Access rights
openAccess
Journal Title
Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
This publication is imported from Aalto University research portal.
View publication in the Research portal
View/Open full text file from the Research portal
Other link related to publication
View publication in the Research portal
View/Open full text file from the Research portal
Other link related to publication
Date
2022-08
Major/Subject
Mcode
Degree programme
Language
en
Pages
Series
Nanomaterials, Volume 12, issue 16
Abstract
Carbon-encapsulated iron nanoparticles (Fe@C) with a mean diameter of 15 nm have been synthesized using evaporation–condensation flow–levitation method by the direct iron-carbon gas-phase reaction at high temperatures. Further, Fe@C were stabilized with bovine serum albumin (BSA) coating, and their electromagnetic properties were evaluated to test their performance in magnetic hyperthermia therapy (MHT) through a specific absorption rate (SAR). Heat generation was observed at different Fe@C concentrations (1, 2.5, and 5 mg/mL) when applied 331 kHz and 60 kA/m of an alternating magnetic field, resulting in SAR values of 437.64, 129.36, and 50.4 W/g for each concentration, respectively. Having such high SAR values at low concentrations, obtained material is ideal for use in MHT.Description
Publisher Copyright: © 2022 by the authors.
Keywords
core–shell nanoparticles, ferromagnetic particles, flow-levitation method, iron nanoparticles, magnetic hyperthermia
Other note
Citation
Ramírez-Morales, M A, Goldt, A E, Kalachikova, P M, Ramirez B, J A, Suzuki, M, Zhigach, A N, Ben Salah, A, Shurygina, L I, Shandakov, S D, Zatsepin, T, Krasnikov, D V, Maekawa, T, Nikolaev, E N & Nasibulin, A G 2022, ' Albumin Stabilized Fe@C Core–Shell Nanoparticles as Candidates for Magnetic Hyperthermia Therapy ', Nanomaterials, vol. 12, no. 16, 2869 . https://doi.org/10.3390/nano12162869
