Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorThiede, A.
dc.contributor.authorParkkonen, L.
dc.contributor.authorVirtala, P.
dc.contributor.authorLaasonen, M.
dc.contributor.authorMäkelä, Jyrki P.
dc.contributor.authorKujala, T.
dc.contributor.departmentUniversity of Helsinki
dc.contributor.departmentDepartment of Neuroscience and Biomedical Engineering
dc.contributor.departmentHelsinki University Central Hospital
dc.date.accessioned2020-09-11T06:29:48Z
dc.date.available2020-09-11T06:29:48Z
dc.date.issued2020-08
dc.description.abstractPoor neural speech discrimination has been connected to dyslexia, and may represent phonological processing deficits that are hypothesized to be the main cause for reading impairments. Thus far, neural speech discrimination impairments have rarely been investigated in adult dyslexics, and even less by examining sources of neuromagnetic responses. We compared neuromagnetic speech discrimination in dyslexic and typical readers with mismatch fields (MMF) and determined the associations between MMFs and reading-related skills. We expected weak and atypically lateralized MMFs in dyslexic readers, and positive associations between reading-related skills and MMF strength. MMFs were recorded to a repeating pseudoword /ta-ta/ with occasional changes in vowel identity, duration, or syllable frequency from 43 adults, 21 with confirmed dyslexia. Phonetic (vowel and duration) changes elicited left-lateralized MMFs in the auditory cortices. Contrary to our hypothesis, MMF source strengths or lateralization did not differ between groups. However, better verbal working memory was associated with stronger left-hemispheric MMFs to duration changes across groups, and better reading was associated with stronger right-hemispheric late MMFs across speech-sound changes in dyslexic readers. This suggests a link between neural speech processing and reading-related skills, in line with previous work. Furthermore, our findings suggest a right-hemispheric compensatory mechanism for language processing in dyslexia. The results obtained promote the use of MMFs in investigating reading-related brain processes.en
dc.description.versionPeer revieweden
dc.format.extent12
dc.format.mimetypeapplication/pdf
dc.identifier.citationThiede , A , Parkkonen , L , Virtala , P , Laasonen , M , Mäkelä , J P & Kujala , T 2020 , ' Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers ' , Heliyon , vol. 6 , no. 8 , e04619 . https://doi.org/10.1016/j.heliyon.2020.e04619en
dc.identifier.doi10.1016/j.heliyon.2020.e04619
dc.identifier.issn2405-8440
dc.identifier.otherPURE UUID: 3c62153e-b746-4116-a9a6-ccc4912a8aee
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/3c62153e-b746-4116-a9a6-ccc4912a8aee
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85089739657&partnerID=8YFLogxK
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/51270979/Thiede_Neuromagnetic_speech_discrimination.1_s2.0_S2405844020314638_main.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/46416
dc.identifier.urnURN:NBN:fi:aalto-202009115339
dc.language.isoenen
dc.publisherElsevier
dc.relation.ispartofseriesHeliyonen
dc.relation.ispartofseriesVolume 6, issue 8en
dc.rightsopenAccessen
dc.subject.keywordApplied linguistics
dc.subject.keywordBehavioral neuroscience
dc.subject.keywordClinical psychology
dc.subject.keywordCognitive neuroscience
dc.subject.keywordCognitive psychology
dc.subject.keywordDyslexia
dc.subject.keywordMagnetoencephalography (MEG)
dc.subject.keywordMismatch field (MMF)
dc.subject.keywordReading skills
dc.subject.keywordSpeech processing
dc.subject.keywordVerbal working memory
dc.titleNeuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readersen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
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