Microwave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcohols

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dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorDhokale, Bhausaheben_US
dc.contributor.authorSusarrey-Arce, Arturoen_US
dc.contributor.authorPekkari, Annaen_US
dc.contributor.authorRunemark, Augusten_US
dc.contributor.authorMoth-Poulsen, Kasperen_US
dc.contributor.authorLanghammer, Christophen_US
dc.contributor.authorHärelind, Hannaen_US
dc.contributor.authorBusch, Michaelen_US
dc.contributor.authorVandichel, Matthiasen_US
dc.contributor.authorSundén, Henriken_US
dc.contributor.departmentDepartment of Chemistry and Materials Scienceen
dc.contributor.groupauthorComputational Chemistryen
dc.contributor.organizationChalmers University of Technologyen_US
dc.date.accessioned2020-12-31T08:46:20Z
dc.date.available2020-12-31T08:46:20Z
dc.date.issued2020-12-16en_US
dc.description.abstractThe development of cheap and robust heterogeneous catalysts for the Meerwein-Ponndorf-Verley (MPV) reduction is desirable due to the difficulties in product isolation and catalyst recovery associated with the traditional use of homogeneous catalysts for MPV. Herein, we show that microwave heated γ-Al2O3 can be used for the reduction of aldehydes to alcohols. The reaction is efficient and has a broad substrates scope (19 entries). The products can be isolated by simple filtration, and the catalyst can be regenerated. With the use of microwave heating, we can direct the heating to the catalyst rather than to the whole reaction medium. Furthermore, DFT was used to study the reaction mechanism, and we can conclude that a dual-site mechanism is operative where the aldehyde and 2-propoxide are situated on two adjacent Al sites during the reduction. Additionally, volcano plots were used to rationalize the reactivity of Al2O3 in comparison to other metal oxides.en
dc.description.versionPeer revieweden
dc.format.extent12
dc.format.extent6344-6355
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationDhokale, B, Susarrey-Arce, A, Pekkari, A, Runemark, A, Moth-Poulsen, K, Langhammer, C, Härelind, H, Busch, M, Vandichel, M & Sundén, H 2020, ' Microwave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcohols ', ChemCatChem, vol. 12, no. 24, pp. 6344-6355 . https://doi.org/10.1002/cctc.202001284en
dc.identifier.doi10.1002/cctc.202001284en_US
dc.identifier.issn1867-3880
dc.identifier.otherPURE UUID: aac72a7b-9481-4984-b85b-baa7aefb11deen_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/aac72a7b-9481-4984-b85b-baa7aefb11deen_US
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85093839878&partnerID=8YFLogxKen_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/54454118/cctc.202001284.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/101585
dc.identifier.urnURN:NBN:fi:aalto-2020123160406
dc.language.isoenen
dc.publisherWILEY-V C H VERLAG GMBH
dc.relation.ispartofseriesChemCatChemen
dc.relation.ispartofseriesVolume 12, issue 24en
dc.rightsopenAccessen
dc.subject.keywordMicrowave-assisted catalysisen_US
dc.subject.keywordMPV reductionen_US
dc.subject.keywordγ-AlOen_US
dc.titleMicrowave-heated γ-Alumina Applied to the Reduction of Aldehydes to Alcoholsen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
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[article-cris] Kemian tekniikan korkeakoulu / CHEM