A DNA Origami-Based Chiral Plasmonic Sensing Device

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorHuang, Yikeen_US
dc.contributor.authorNguyen, Khaen_US
dc.contributor.authorNatarajan, Ashwinen_US
dc.contributor.authorKuzyk, Antonen_US
dc.contributor.departmentDepartment of Neuroscience and Biomedical Engineeringen
dc.date.accessioned2019-01-30T15:10:05Z
dc.date.available2019-01-30T15:10:05Z
dc.date.issued2018-12-26en_US
dc.description.abstractAccurate and reliable biosensing is crucial for environmental monitoring, food safety, and diagnostics. Spatially reconfigurable DNA origami nanostructures are excellent candidates for the generation of custom sensing probes. Here we present a nanoscale biosensing device that combines the accuracy and precision of the DNA origami nanofabrication technique, unique optical responses of chiral plasmonic assemblies, and high affinity and selectivity of aptamers. This combination enables selective and sensitive detection of targets even in strongly absorbing fluids. We expect that the presented sensing scheme can be adapted to a wide range of analytes and tailored to specific needs.en
dc.description.versionPeer revieweden
dc.format.extent44221-44225
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationHuang, Y, Nguyen, K, Natarajan, A & Kuzyk, A 2018, ' A DNA Origami-Based Chiral Plasmonic Sensing Device ', ACS Applied Materials and Interfaces, vol. 10, no. 51, pp. 44221-44225 . https://doi.org/10.1021/acsami.8b19153en
dc.identifier.doi10.1021/acsami.8b19153en_US
dc.identifier.issn1944-8244
dc.identifier.issn1944-8252
dc.identifier.otherPURE UUID: 94c9c09e-c380-4932-8072-330ff99dc310en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/94c9c09e-c380-4932-8072-330ff99dc310en_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/31281155/acsami.8b19153.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/36281
dc.identifier.urnURN:NBN:fi:aalto-201901301451
dc.language.isoenen
dc.publisherAMER CHEMICAL SOC
dc.relation.ispartofseriesACS Applied Materials and Interfacesen
dc.relation.ispartofseriesVolume 10, issue 51en
dc.rightsopenAccessen
dc.subject.keywordaptamersen_US
dc.subject.keywordbiosensingen_US
dc.subject.keywordchiral plasmonicsen_US
dc.subject.keywordDNA origamien_US
dc.subject.keywordgold nanorodsen_US
dc.titleA DNA Origami-Based Chiral Plasmonic Sensing Deviceen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
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