Localization of Syntactic and Semantic Brain Responses using Magnetoencephalography

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorService, Elisabet
dc.contributor.authorHelenius, Päivi
dc.contributor.authorMaury, Sini
dc.contributor.authorSalmelin, Riitta
dc.contributor.departmentNeurotieteen ja lääketieteellisen tekniikan laitosfi
dc.contributor.departmentDepartment of Neuroscience and Biomedical Engineeringen
dc.contributor.schoolPerustieteiden korkeakoulufi
dc.contributor.schoolSchool of Scienceen
dc.date.accessioned2015-05-18T09:00:39Z
dc.date.available2015-05-18T09:00:39Z
dc.date.issued2007
dc.description.abstractElectrophysiological methods have been used to study the temporal sequence of syntactic and semantic processing during sentence comprehension. Two responses associated with syntactic violations are the left anterior negativity (LAN) and the P600. A response to semantic violation is the N400. Although the sources of the N400 response have been identified in the left (and right) temporal lobe, the neural signatures of the LAN and P600 have not been revealed. The present study used magnetoencephalography to localize sources of syntactic and semantic activation in Finnish sentence reading. Participants were presented with sentences that ended in normally inf lected nouns, nouns in an unacceptable case, verbs instead of nouns, or nouns that were correctly inflected but made no sense in the context. Around 400 msec, semantically anomalous last words evoked strong activation in the left superior temporal lobe with significant activation also for word class errors (N400). Weaker activation was seen for the semantic errors in the right hemisphere. Later, 600-800 msec after word onset, the strongest activation was seen to word class and morphosyntactic errors (P600). Activation was significantly weaker to semantically anomalous and correct words. The P600 syntactic activation was localized to bilateral sources in the temporal lobe, posterior to the N400 sources. The results suggest that the same general region of the superior temporal cortex gives rise to both LAN and N400 with bilateral reactivity to semantic manipulation and a left hemisphere effect to syntactic manipulation. The bilateral P600 response was sensitive to syntactic but not semantic factors.en
dc.description.versionPeer revieweden
dc.format.extent1193-1205
dc.format.mimetypeapplication/pdfen
dc.identifier.citationService, Elisabet & Helenius, Päivi & Maury, Sini & Salmelin, Riitta. 2007. Localization of Syntactic and Semantic Brain Responses using Magnetoencephalography. Journal of Cognitive Neuroscience. Volume 19, Issue 7. P. 1193-1205. ISSN 0898-929X (printed). DOI: 10.1162/jocn.2007.19.7.1193.en
dc.identifier.doi10.1162/jocn.2007.19.7.1193
dc.identifier.issn0898-929X (printed)
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/16064
dc.identifier.urnURN:NBN:fi:aalto-201505182707
dc.language.isoenen
dc.publisherMIT Pressen
dc.relation.ispartofseriesJournal of Cognitive Neuroscienceen
dc.relation.ispartofseriesVolume 19, Issue 7
dc.rights© 2007 MIT Press. This is the final version of the article: Service, Elisabet ; Helenius, Päivi ; Maury, Sini ; Salmelin, Riitta. 2007. Localization of Syntactic and Semantic Brain Responses using Magnetoencephalography. Journal of Cognitive Neuroscience. Volume 19, Issue 7. P. 1193-1205. ISSN 0898-929X (printed). DOI: 10.1162/jocn.2007.19.7.1193, which has been published in final form at http://www.mitpressjournals.org/doi/abs/10.1162/jocn.2007.19.7.1193#.VVlvIGOkuSoen
dc.rights.holderMIT Press
dc.subject.keywordmagnetoencephalographyen
dc.subject.keywordelectrophysiological methoden
dc.subject.keywordsyntactic and semantic brainen
dc.subject.otherLinguisticsen
dc.subject.otherMedical sciencesen
dc.titleLocalization of Syntactic and Semantic Brain Responses using Magnetoencephalographyen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.dcmitypetexten
dc.type.versionFinal published versionen
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
A1_service_elisabet_2007.pdf
Size:
414.66 KB
Format:
Adobe Portable Document Format