Highly Chemoselective Copper-Catalyzed Conjugate Reduction of Stereochemically Labile alpha,beta-Unsaturated Amino Ketones

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Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2009

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Language

en

Pages

7598-7601

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JOURNAL OF ORGANIC CHEMISTRY, Volume 74, issue 19

Abstract

Highly chemoselective conjugate reduction of chiral R,β-unsaturated amino ketones has been developed by using triisopropyl phosphite ligated copper hydride complex. The highlights of the method are wide substrate compatibility and exceptional chemoselectivity.

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Citation

Pelss , A , Kumpulainen , E T T & Koskinen , A M P 2009 , ' Highly Chemoselective Copper-Catalyzed Conjugate Reduction of Stereochemically Labile alpha,beta-Unsaturated Amino Ketones ' , Journal of Organic Chemistry , vol. 74 , no. 19 , pp. 7598-7601 . https://doi.org/10.1021/jo9017588