Effects of leaflet curvature and thickness on the crimping stresses in transcatheter heart valve
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Journal Title
Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date
2023-07
Major/Subject
Mcode
Degree programme
Language
en
Pages
8
Series
Journal of Biomechanics, Volume 156
Abstract
With the current advances and expertise in biomedical device technologies, transcatheter heart valves (THVs) have been drawing significant attention. Various studies have been carried out on their durability and damage by dynamic loading in operational conditions. However, very few numerical investigations have been conducted to understand the effects of leaflet curvature and thickness on the crimping stresses which arise during the surgical preparation processes. In order to contribute to the current state of the art, a full heart valve model was presented, the leaflet curvature and thickness of which were then parameterized so as to understand the stress generation as a result of the crimping procedure during the surgical preparations. The results show that the existence of stresses is inevitable during the crimping procedure, which is a reduction factor for valve durability. Especially, stresses on the leaflets at the suture sites connected with the skirt were deduced to be critical and may result in leaflet ruptures after THV implantation.Description
Funding Information: Supports of the Institute for Digital Research and Education (IDRE) at the University of California, Los Angeles (UCLA), United States and Aalto University Seed Funding are gratefully acknowledged. Publisher Copyright: © 2023 The Author(s)
Keywords
Crimping, Finite element analysis (FEA), Leaflet curvature, Leaflet thickness, Transcatheter heart valve (THV)
Other note
Citation
Karakoç , A , Aksoy , O & Taciroğlu , E 2023 , ' Effects of leaflet curvature and thickness on the crimping stresses in transcatheter heart valve ' , Journal of Biomechanics , vol. 156 , 111663 . https://doi.org/10.1016/j.jbiomech.2023.111663
