Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics

The dynamic underwater chemistry seen in nature is inspiring for the next generation of eco-friendly nanochemistry. In this context, green synthesis of size-tailored nanoparticles in a facile and scalable manner via a dynamic process is an interesting challenge. Simulating the volcano-induced dynamic chemistry of the deep ocean, here we demonstrate the Leidenfrost dynamic chemistry occurring in an underwater overheated confined zone as a new tool for customized creation of nanoclusters of zinc peroxide. The hydrodynamic nature of the phenomenon ensures eruption of the nanoclusters towards a much colder region, giving rise to growth of monodisperse, size-tailored nanoclusters. Such nanoparticles are investigated in terms of their cytotoxicity on suspension and adherent cells to prove their applicability as cancer nanotherapeutics. Our research can pave the way for employment of the dynamic green nanochemistry in facile, scalable fabrication of size-tailored nanoparticles for biomedical applications.

DOI

10.1038/ncomms15319

Citation

Elbahri, M, Abdelaziz, R, Disci-Zayed, D, Homaeigohar, S, Sosna, J, Adam, D, Kienle, L, Dankwort, T & Abdelaziz, M 2017, ' Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics ', Nature Communications, vol. 8, 15319 . https://doi.org/10.1038/ncomms15319

Permanent link to this item

https://urn.fi/URN:NBN:fi:aalto-201706205714

Collections

[article-cris] Kemian tekniikan korkeakoulu / CHEM

Show all metadata

Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics

Access rights

URL

Journal Title

Journal ISSN

Volume Title

Authors

Date

Department

Major/Subject

Mcode

Degree programme

Language

Pages

Series

Abstract

Description

Keywords

Other note

DOI

Citation

Permanent link to this item

Collections