Bioinspired lubricating films of cellulose nanofibrils and hyaluronic acid

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dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorValle-Delgado, Juan Joseen_US
dc.contributor.authorJohansson, Leena-Siskoen_US
dc.contributor.authorÖsterberg, Monikaen_US
dc.contributor.departmentDepartment of Forest Products Technologyen
dc.contributor.groupauthorBioproduct Chemistryen
dc.date.accessioned2017-01-19T10:51:18Z
dc.date.embargoinfo:eu-repo/date/embargoEnd/2017-03-01en_US
dc.date.issued2016-02-01en_US
dc.description.abstractThe development of materials that combine the excellent mechanical strength of cellulose nanofibrils (CNF) with the lubricating properties of hyaluronic acid (HA) is a new, promising approach to cartilage implants not explored so far. A simple, solvent-free method to produce a very lubricating, strong cellulosic material by covalently attaching HA to the surface of CNF films is described in this work. A detailed analysis of the tribological properties of the CNF films with and without HA is also presented. Surface and friction forces at micro/nanoscale between model hard surfaces (glass microspheres) and the CNF thin films were measured using an atomic force microscope and the colloid probe technique. The effect of HA attachment, the pH and the ionic strength of the aqueous medium on the forces was examined. Excellent lubrication was observed for CNF films with HA attached in conditions where the HA layer was highly hydrated. These results pave the way for the development of new nanocellulose-based materials with good lubrication properties that could be used in biomedical applications. (C) 2015 Elsevier B.V. All rights reserved.en
dc.description.versionPeer revieweden
dc.format.extent8
dc.format.extent86-93
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationValle-Delgado, J J, Johansson, L-S & Österberg, M 2016, ' Bioinspired lubricating films of cellulose nanofibrils and hyaluronic acid ', Colloids and Surfaces B: Biointerfaces, vol. 138, pp. 86-93 . https://doi.org/10.1016/j.colsurfb.2015.11.047en
dc.identifier.doi10.1016/j.colsurfb.2015.11.047en_US
dc.identifier.issn0927-7765
dc.identifier.issn1873-4367
dc.identifier.otherPURE UUID: 229c50a1-961a-4222-8bae-83d47c7a5d18en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/229c50a1-961a-4222-8bae-83d47c7a5d18en_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/6735782/Online_paper.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/24171
dc.identifier.urnURN:NBN:fi:aalto-201701191116
dc.language.isoenen
dc.relation.ispartofseriesCOLLOIDS AND SURFACES B: BIOINTERFACESen
dc.relation.ispartofseriesVolume 138en
dc.rightsopenAccessen
dc.subject.keywordCellulose nanofibrilsen_US
dc.subject.keywordHyaluronic aciden_US
dc.subject.keywordThin filmsen_US
dc.subject.keywordLubricationen_US
dc.subject.keywordColloid probe techniqueen_US
dc.titleBioinspired lubricating films of cellulose nanofibrils and hyaluronic aciden
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
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[article-cris] Kemian tekniikan korkeakoulu / CHEM