Hajos-Parrish ketone: approaches toward C-ring prcursors of 7-deoxytaxol

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dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorLajunen, M.
dc.contributor.authorKoskinen, A.
dc.contributor.departmentDepartment of Chemistryen
dc.date.accessioned2016-09-23T08:16:42Z
dc.date.issued2000
dc.description.abstractTwo routes were evaluated for the preparation of multiply functionalized cyclohexane derivatives in a stereocontrolled fashion from readily available Hajos–Parrish ketone 1. Reduction (catalytic or dissolving metal) led to the cis-isomer 8, in stark contrast to previous literature. Finally, modification of earlier steroid chemistry allowed the synthesis of the trans-isomer 14. The latter is a useful intermediate for the synthesis of 7-deoxytaxol derivatives.en
dc.description.versionPeer revieweden
dc.format.extent1439-1443
dc.format.mimetypeapplication/pdf
dc.identifier.citationLajunen , M & Koskinen , A 2000 , ' Hajos-Parrish ketone: approaches toward C-ring prcursors of 7-deoxytaxol ' , Journal of the Chemical Society, Perkin Transactions 1 , no. 1 , pp. 1439-1443 . https://doi.org/10.1039/a909471gen
dc.identifier.doi10.1039/a909471g
dc.identifier.otherPURE UUID: 8896995d-4bef-429a-83d7-6388a25cc00d
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/8896995d-4bef-429a-83d7-6388a25cc00d
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/7159156/ms076.PDF
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/22321
dc.identifier.urnURN:NBN:fi:aalto-201609234325
dc.language.isoenen
dc.relation.ispartofseriesJournal Chem. Soc., Perkin Trans.en
dc.relation.ispartofseriesissue 1en
dc.rightsopenAccessen
dc.subject.keywordsynthesis
dc.subject.keywordtaxol
dc.titleHajos-Parrish ketone: approaches toward C-ring prcursors of 7-deoxytaxolen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionacceptedVersion

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