Microfibers synthesized by wet-spinning of chitin nanomaterials : Mechanical, structural and cell proliferation properties
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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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en
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10
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RSC Advances, Volume 10, issue 49, pp. 29450-29459
Abstract
Partially deacetylated chitin nanofibers (ChNF) were isolated from shell residues derived from crab biomass and used to prepare hydrogels, which were easily transformed into continuous microfibers by wet-spinning. We investigated the effect of ChNF solid content, extrusion rate and coagulant type, which included organic (acetone) and alkaline (NaOH and ammonia) solutions, on wet spinning. The properties of the microfibers and associated phenomena were assessed by tensile strength, quartz crystal microgravimetry, dynamic vapor sorption (DVS), thermogravimetric analysis and wide-angle X-ray scattering (WAXS). The as-spun microfibers (14 GPa stiffness) comprised hierarchical structures with fibrils aligned in the lateral direction. The microfibers exhibited a remarkable water sorption capacity (up to 22 g g(-1)), while being stable in the wet state (50% of dry strength), which warrants consideration as biobased absorbent systems. In addition, according to cell proliferation and viability of rat cardiac myoblast H9c2 and mouse bone osteoblast K7M2, the wet-spun ChNF microfibers showed excellent results and can be considered as fully safe for biomedical uses, such as in sutures, wound healing patches and cell culturing.Description
| openaire: EC/H2020/788489/EU//BioELCell
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Wang, L, Ezazi, N Z, Liu, L, Ajdary, R, Xiang, W, Borghei, M, Santos, H A & Rojas, O J 2020, 'Microfibers synthesized by wet-spinning of chitin nanomaterials : Mechanical, structural and cell proliferation properties', RSC Advances, vol. 10, no. 49, pp. 29450-29459. https://doi.org/10.1039/d0ra06178f