Ionic current inversion in pressure-driven polymer translocation through nanopores

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorBuyukdagli, S.
dc.contributor.authorBlossey, R.
dc.contributor.authorAla-Nissila, Tapio
dc.contributor.departmentDepartment of Applied Physicsen
dc.date.accessioned2016-09-23T08:17:53Z
dc.date.issued2015
dc.description.abstractWe predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field electrostatics. In the presence of multivalent counterions, electrostatic many-body effects result in the reversal of the DNA charge. The attraction of anions to the charge-inverted DNA molecule reverses the sign of the ionic current through the pore. Our theory allows for a comprehensive understanding of the complex features of the resulting streaming currents. The underlying mechanism is an efficient way to detect DNA charge reversal in pressure-driven translocation experiments with multivalent cations.en
dc.description.versionPeer revieweden
dc.format.extent1-5
dc.format.mimetypeapplication/pdf
dc.identifier.citationBuyukdagli , S , Blossey , R & Ala-Nissila , T 2015 , ' Ionic current inversion in pressure-driven polymer translocation through nanopores ' , Physical Review Letters , vol. 114 , no. 8 , 088303 , pp. 1-5 . https://doi.org/10.1103/PhysRevLett.114.088303en
dc.identifier.doi10.1103/PhysRevLett.114.088303
dc.identifier.issn0031-9007
dc.identifier.issn1079-7114
dc.identifier.otherPURE UUID: ac7c1661-60e4-4f09-9786-bdc717f8b58a
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/ac7c1661-60e4-4f09-9786-bdc717f8b58a
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/4304725/PhysRevLett.114.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/22339
dc.identifier.urnURN:NBN:fi:aalto-201609234343
dc.language.isoenen
dc.relation.ispartofseriesPHYSICAL REVIEW LETTERSen
dc.relation.ispartofseriesVolume 114, issue 8en
dc.rightsopenAccessen
dc.subject.keywordcharged liquid
dc.subject.keywordpolymer translocation
dc.titleIonic current inversion in pressure-driven polymer translocation through nanoporesen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
Files