Toxicities of detergents used in cleaning chemicals and hygiene products in a test battery of ex vivo and in vitro assays

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dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorAndersson, Ainoen_US
dc.contributor.authorSzabolcs, Nagyen_US
dc.contributor.authorMikkola, Raimoen_US
dc.contributor.authorKurnitski, Jareken_US
dc.contributor.authorSalonen, Heidien_US
dc.contributor.departmentDepartment of Civil Engineeringen
dc.contributor.editorAhola, Mervien_US
dc.contributor.editorMerikari, Annaen_US
dc.contributor.groupauthorStructures – Structural Engineering, Mechanics and Computationen
dc.contributor.organizationUniversity of Pannoniaen_US
dc.date.accessioned2020-01-17T13:27:51Z
dc.date.available2020-01-17T13:27:51Z
dc.date.issued2019en_US
dc.description.abstractFive synthetic surfactants used as detergents in cleaning chemicals and hygiene products were selected to test their In vivo and Ex vivo toxicity. The toxicity of one anionic detergent (SDS), one cationic detergent (DDDAC) and three non-ionic detergents (TWEEN 80, triton X-100, genapol X-080) was tested with boar spermatozoa (4 Ex Vivo assays) and PK-15 porcine kidney cells (4 In Vivo assays). The reference toxin used was triclosan (biocide). The results revealed a characteristic toxicity profile for each detergent. The detergents toxicity from most to least toxic was as follow: DDDAC > genapol X-080 > triclosan > triton x-100 > SDS > TWEEN 80. The results also showed that mitochondrial toxicity -measured as acceleration of glucose consumption-was detected for genapol X-080, DDAC and triclosan but not for TWEEN 80.en
dc.description.versionPeer revieweden
dc.format.extent297-302
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationAndersson, A, Szabolcs, N, Mikkola, R, Kurnitski, J & Salonen, H 2019, Toxicities of detergents used in cleaning chemicals and hygiene products in a test battery of ex vivo and in vitro assays . in M Ahola & A Merikari (eds), Sisäilmastoseminaari 2019 : Sisäilmayhdistys raportti 37 . SIY raportti, no. 37, SIY Sisäilmatieto Oy, pp. 297-302, Sisäilmastoseminaari, Helsinki, Finland, 14/03/2019 .en
dc.identifier.isbn978-952-5236-49-1
dc.identifier.issn1237-1866
dc.identifier.otherPURE UUID: 5c7e3cf0-035a-4e70-8253-a4ae412f9e0aen_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/5c7e3cf0-035a-4e70-8253-a4ae412f9e0aen_US
dc.identifier.otherPURE LINK: https://www.sisailmauutiset.fi/Sisailmastoseminaari_2019.pdfen_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/40181478/Salonen_artik4.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/42515
dc.identifier.urnURN:NBN:fi:aalto-202001171630
dc.language.isoenen
dc.publisherSisäilmayhdistys ry
dc.relation.ispartofSisäilmastoseminaarien
dc.relation.ispartofseriesSisäilmastoseminaari 2019en
dc.relation.ispartofseriesSIY raporttien
dc.relation.ispartofseriesissue 37en
dc.rightsopenAccessen
dc.titleToxicities of detergents used in cleaning chemicals and hygiene products in a test battery of ex vivo and in vitro assaysen
dc.typeA3 Kirjan tai muun kokoomateoksen osafi
dc.type.versionpublishedVersion

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