Toxicities of detergents used in cleaning chemicals and hygiene products in a test battery of ex vivo and in vitro assays
Loading...
Access rights
openAccess
URL
Journal Title
Journal ISSN
Volume Title
A3 Kirjan tai muun kokoomateoksen osa
This publication is imported from Aalto University research portal.
View publication in the Research portal (opens in new window)
View/Open full text file from the Research portal (opens in new window)
Other link related to publication (opens in new window)
View publication in the Research portal (opens in new window)
View/Open full text file from the Research portal (opens in new window)
Other link related to publication (opens in new window)
Date
2019
Department
Major/Subject
Mcode
Degree programme
Language
en
Pages
297-302
Series
Sisäilmastoseminaari 2019, SIY raportti, issue 37
Abstract
Five synthetic surfactants used as detergents in cleaning chemicals and hygiene products were selected to test their In vivo and Ex vivo toxicity. The toxicity of one anionic detergent (SDS), one cationic detergent (DDDAC) and three non-ionic detergents (TWEEN 80, triton X-100, genapol X-080) was tested with boar spermatozoa (4 Ex Vivo assays) and PK-15 porcine kidney cells (4 In Vivo assays). The reference toxin used was triclosan (biocide). The results revealed a characteristic toxicity profile for each detergent. The detergents toxicity from most to least toxic was as follow: DDDAC > genapol X-080 > triclosan > triton x-100 > SDS > TWEEN 80. The results also showed that mitochondrial toxicity -measured as acceleration of glucose consumption-was detected for genapol X-080, DDAC and triclosan but not for TWEEN 80.Description
Keywords
Other note
Citation
Andersson, A, Szabolcs, N, Mikkola, R, Kurnitski, J & Salonen, H 2019, Toxicities of detergents used in cleaning chemicals and hygiene products in a test battery of ex vivo and in vitro assays . in M Ahola & A Merikari (eds), Sisäilmastoseminaari 2019 : Sisäilmayhdistys raportti 37 . SIY raportti, no. 37, SIY Sisäilmatieto Oy, pp. 297-302, Sisäilmastoseminaari, Helsinki, Finland, 14/03/2019 .