Hygiene monitoring biosensing systems in hospital environments

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.advisorAnttila, Veli-Jukka; M.D.
dc.contributor.authorKöhler, Sebastian
dc.contributor.departmentDepartment of Electrical and Communications Engineeringen
dc.contributor.departmentSähkö- ja tietoliikennetekniikan osastofi
dc.contributor.labLaboratory of Computational Engineeringen
dc.contributor.labLaskennallisen tekniikan laboratoriofi
dc.contributor.supervisorTulkki, Jukka; Prof.
dc.date.accessioned2011-12-08T09:14:48Z
dc.date.available2011-12-08T09:14:48Z
dc.date.issued2006
dc.description.abstractThis thesis concerns the monitoring of biogenic impurities and hygiene in hospital environments by means of biosensing systems. The objective is to find biosensing systems applicable in hospital environments and able to identify pathogens that cause nosocomial infections, on surfaces, in the air and water. In the first part of the thesis, nosocomial infections were investigated, along with their prevalence, mortality, financial aspects and the most common microorganisms causing them. Furthermore. existing national and international nosocomial infection surveillance programmes, as well as organisations and journals associated with this field, were pinned down. Collaboration with the Meilahti Helsinki University Central Hospital enabled examination of their nosocomial infection status and familiarisation with their current prevention practices. The most important is good hand hygiene, trailed by, among others, pressurisation and filtration of air; limited use of tap water; and good overall cleanliness. Products that monitor or test the hygiene level are not in routine use. Three areas, where biosensing systems could be of use in a hospital, were identified. These are the ventilation system, the water distribution system and cleaning. The second part of the thesis discusses biosensing systems. Various methods were mapped in an overview of this field, comprising electrochemical, optical, microelectromechanical, nucleic acid- and cell-based systems. Based on this, the most promising methods – laser- and light-emitting diode-induced fluorescence and biocavity lasing – were explored further. These have the potential to detect microbes eminently fast, even in real time. Use of the fluorescence method to verify the functioning of filters in the ventilation system has been evaluated, as well as the biocavity laser's potential to validate the purity of water and the cleanliness of surfaces in conjunction with cleaning. Rapid biosensing systems based on the aforementioned novel methods are also applicable to, among others, flow cytometry devices used for gene sequencing.en
dc.format.extent90
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/936
dc.identifier.urnurn:nbn:fi:tkk-007335
dc.language.isoenen
dc.locationP1fi
dc.programmeElektroniikan ja sähkötekniikan koulutusohjelmafi
dc.programme.majorLaskennallinen tekniikkafi
dc.programme.mcodeS-114
dc.publisherHelsinki University of Technologyen
dc.publisherTeknillinen korkeakoulufi
dc.rights.accesslevelopenAccess
dc.subject.keywordbiosensing systemsen
dc.subject.keywordhygiene monitoringen
dc.subject.keywordbiosensoren
dc.subject.keywordnosocomial infectionen
dc.subject.keywordhospitalen
dc.subject.keywordmicrobeen
dc.subject.keyworddetectionen
dc.subject.keywordbiosensorsystemsv
dc.subject.keywordhygienövervakningsv
dc.subject.keywordbiosensorsv
dc.subject.keywordsjukhusinfektionsv
dc.subject.keywordsjukhussv
dc.subject.keywordmikrobsv
dc.subject.keyworddetektionsv
dc.subject.otherElectrical engineeringen
dc.subject.otherMedical sciencesen
dc.titleHygiene monitoring biosensing systems in hospital environmentsen
dc.typeG2 Pro gradu, diplomityöfi
dc.type.dcmitypetexten
dc.type.okmG2 Pro gradu, diplomityö
dc.type.ontasotDiplomityöfi
dc.type.ontasotMaster's thesisen
dc.type.publicationmasterThesis
local.aalto.digifolderAalto_36568
local.aalto.idinssi32763
local.aalto.openaccessyes

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
urn007335.pdf
Size:
1.92 MB
Format:
Adobe Portable Document Format