Requirements for Coregistration Accuracy in On-Scalp MEG

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorZetter, Rasmusen_US
dc.contributor.authorIivanainen, Joonasen_US
dc.contributor.authorStenroos, Mattien_US
dc.contributor.authorParkkonen, Laurien_US
dc.contributor.departmentDepartment of Neuroscience and Biomedical Engineeringen
dc.date.accessioned2018-12-10T10:29:29Z
dc.date.available2018-12-10T10:29:29Z
dc.date.issued2018-11en_US
dc.description| openaire: EC/H2020/678578/EU//HRMEG
dc.description.abstractRecent advances in magnetic sensing has made on-scalp magnetoencephalography (MEG) possible. In particular, optically-pumped magnetometers (OPMs) have reached sensitivity levels that enable their use in MEG. In contrast to the SQUID sensors used in current MEG systems, OPMs do not require cryogenic cooling and can thus be placed within millimetres from the head, enabling the construction of sensor arrays that conform to the shape of an individual’s head. To properly estimate the location of neural sources within the brain, one must accurately know the position and orientation of sensors in relation to the head. With the adaptable on-scalp MEG sensor arrays, this coregistration becomes more challenging than in current SQUID-based MEG systems that use rigid sensor arrays. Here, we used simulations to quantify how accurately one needs to know the position and orientation of sensors in an on-scalp MEG system. The effects that different types of localisation errors have on forward modelling and source estimates obtained by minimum-norm estimation, dipole fitting, and beamforming are detailed. We found that sensor position errors generally have a larger effect than orientation errors and that these errors affect the localisation accuracy of superficial sources the most. To obtain similar or higher accuracy than with current SQUID-based MEG systems, RMS sensor position and orientation errors should be (Formula presented.) and (Formula presented.), respectively.en
dc.description.versionPeer revieweden
dc.format.extent18
dc.format.extent931-948
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationZetter, R, Iivanainen, J, Stenroos, M & Parkkonen, L 2018, ' Requirements for Coregistration Accuracy in On-Scalp MEG ', Brain Topography, vol. 31, no. 6, pp. 931-948 . https://doi.org/10.1007/s10548-018-0656-5en
dc.identifier.doi10.1007/s10548-018-0656-5en_US
dc.identifier.issn0896-0267
dc.identifier.issn1573-6792
dc.identifier.otherPURE UUID: c0520a39-ae30-4eab-9cc9-71b6b23478b9en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/c0520a39-ae30-4eab-9cc9-71b6b23478b9en_US
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85048900710&partnerID=8YFLogxKen_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/29816738/Zetter2018_Article_RequirementsForCoregistrationA.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/35255
dc.identifier.urnURN:NBN:fi:aalto-201812106270
dc.language.isoenen
dc.relationinfo:eu-repo/grantAgreement/EC/H2020/678578/EU//HRMEGen_US
dc.relation.ispartofseriesBrain Topographyen
dc.relation.ispartofseriesVolume 31, issue 6en
dc.rightsopenAccessen
dc.subject.keywordCoregistrationen_US
dc.subject.keywordMagnetoencephalographyen_US
dc.subject.keywordOptically-pumped magnetometeren_US
dc.titleRequirements for Coregistration Accuracy in On-Scalp MEGen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
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