Photophysical properties of chiral semiconductor nanocrystals in biological environments
Loading...
URL
Journal Title
Journal ISSN
Volume Title
Sähkötekniikan korkeakoulu |
Master's thesis
Unless otherwise stated, all rights belong to the author. You may download, display and print this publication for Your own personal use. Commercial use is prohibited.
Authors
Date
2016-08-24
Department
Major/Subject
Micro- and Nanosciences
Mcode
ELEC3037
Degree programme
NanoRad - Master’s Programme in Nano and Radio Sciences (TS2013)
Language
en
Pages
76
Series
Abstract
During the last decade much work has been focused on the use of nanostructures toward problems of biology and medicine. The issue of nanostructures application in cancer therapy depends on the effectiveness of the nanocrystals loading into cells. In this work chiral nanostructures based on CdSe/ZnS quantum dots (QD) and CdSe/CdS quantum dots in quantum rods (DiR) solubilized by L- and D-cysteine were formed using phase transfer method. We studied photophysical properties of chiral nanostructures in different biological media and analyzed spectral luminescent properties of complexes based on chiral nanostructures. Enantioselective cellular uptake of nanostructures was revealed, namely that L-cysteine capped nanocrystals uptake is higher than that of D-cysteine capped nanocrystals. Enantioselective interaction between chiral enantiomers of molecules and chiral nanostructures was detected. We believe this principle may lay the groundwork for novel approaches to studying biological objects and to application of nanostructures in medicine.Description
Supervisor
Sun, ZhipeiThesis advisor
Keywords
nanocrystals, quantum dots, dot-in-rods, chirality, cancer, nanobiotechnology