LAVAA: A lightweight association viewer across ailments
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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date
2023
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en
Pages
7
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Bioinformatics Advances, Volume 3, issue 1
Abstract
Motivation: Biobank scale genetic associations results over thousands of traits can be difficult to visualize and navigate. Results: We have created LAVAA, a visualization web-application to generate genetic volcano plots for simultaneously considering the P-value, effect size, case counts, trait class and fine-mapping posterior probability at a singlenucleotide polymorphism (SNP) across a range of traits from a large set of genome-wide association study. We find that user interaction with association results in LAVAA can enrich and enhance the biological interpretation of individual loci. Availability and implementation: LAVAA is available as a stand-alone web service (https://geneviz.aalto.fi/LAVAA/) and will be available in future releases of the finngen.fi website starting with release 10 in late 2023.Description
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Fauman, E B, Keppo, S, Cerioli, N, Vyas, R, Kurki, M, Daly, M J & Reeve, M P 2023, ' LAVAA: A lightweight association viewer across ailments ', Bioinformatics Advances, vol. 3, no. 1, vbad018 . https://doi.org/10.1093/bioadv/vbad018