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Biosynthetic optical waveguide interface integration using biomimetic - de novo design ELP for optoelectronic applications
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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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en
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11
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Computational and Structural Biotechnology Journal, Volume 33, pp. 13-23
Abstract
The integration of biologically inspired materials into photonic device fabrication offers a promising route toward sustainable and biocompatible alternative to conventional in inorganic or petroleum based synthetic materials used in optoelectronic systems. In this work, we present a biosynthetic approach for waveguide fabrication utilizing a biomimetic - de novo designed elastin-like polypeptide (ELP) formulated into an all-water-based photoresist compatible with two-photon polymerization (2PP). The ELP was genetically engineered and recombinantly produced in microbes for enhanced molecular stability, a critical feature for withstanding both localized and bulk temperature increases that occur during high-intensity laser exposure during printing. The resulting ELP formulation supported direct writing of waveguide architecture without the need for organic solvents, harsh processing steps, or post-functionalization. This aqueous resist formulation exhibits high stability during printing and retains its structural integrity upon curing, making it a promising candidate for environmentally friendly, soft-material photonics. This work establishes a foundation for using biosynthetic polypeptides in the fabrication of functional photonic elements and demonstrates a step toward greener, protein-based optoelectronic manufacturing technologies.
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Publisher Copyright: © 2025 The Authors
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Seisto, A, Hokkanen, A, Damlin, P, Pylkkänen, R, Kiiveri, K, Borisova, A S, Kvarnström, C, Cheng, X, Sun, Z, Nonappa, & Mohammadi, P 2026, 'Biosynthetic optical waveguide interface integration using biomimetic - de novo design ELP for optoelectronic applications', Computational and Structural Biotechnology Journal, vol. 33, pp. 13-23. https://doi.org/10.1016/j.csbj.2025.12.009