Multispectral photon-counting for medical imaging and beam characterization — A project review

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorKirschenmann, S.en_US
dc.contributor.authorBezak, M.en_US
dc.contributor.authorBharthuar, S.en_US
dc.contributor.authorBrücken, E.en_US
dc.contributor.authorEmzir, M.en_US
dc.contributor.authorGolovleva, M.en_US
dc.contributor.authorGädda, A.en_US
dc.contributor.authorKalliokoski, M.en_US
dc.contributor.authorKaradzhinova-Ferrer, A.en_US
dc.contributor.authorKarjalainen, A.en_US
dc.contributor.authorKoponen, P.en_US
dc.contributor.authorKramarenko, N.en_US
dc.contributor.authorLuukka, P.en_US
dc.contributor.authorOtt, J.en_US
dc.contributor.authorPetrow, H.en_US
dc.contributor.authorSiiskonen, T.en_US
dc.contributor.authorSärkkä, S.en_US
dc.contributor.authorTikkanen, J.en_US
dc.contributor.authorTurpeinen, R.en_US
dc.contributor.authorWinkler, A.en_US
dc.contributor.departmentDepartment of Electrical Engineering and Automationen
dc.contributor.groupauthorSensor Informatics and Medical Technologyen
dc.contributor.organizationUniversity of Helsinkien_US
dc.contributor.organizationLUT Universityen_US
dc.contributor.organizationHelsinki Institute of Physicsen_US
dc.contributor.organizationRadiation and Nuclear Safety Authorityen_US
dc.contributor.organizationDetection Technology Oyjen_US
dc.contributor.organizationOkmetic Oyen_US
dc.contributor.organizationUniversity of California, Santa Cruzen_US
dc.date.accessioned2022-08-10T08:16:11Z
dc.date.available2022-08-10T08:16:11Z
dc.date.issued2022-09-11en_US
dc.descriptionFunding Information: The research conducted and presented here was performed in the framework of the Academy of Finland project, number 314473, Multispectral photon-counting for medical imaging and beam characterization, for which we would like to acknowledge the funding. S. Kirschenmann and S. Bharthuar thank the Magnus Ehrnrooth foundation, Finland for financial support. The measurements were performed at the joint Detector Laboratory of the University of Helsinki and the Helsinki Institute of Physics as well as at the Radiation and Nuclear Safety Authority (STUK) and we would like to thank the staff for their support. Publisher Copyright: © 2022 The Authors
dc.description.abstractCentral focus of the MPMIB project – funded via the Academy of Finland's RADDESS 2018–2021 programme – has been research towards a next-generation radiation detection system operating in a photon-counting (PC) multispectral mode: The extraction of energy spectrum per detector pixel data will lead to better efficacy in medical imaging with ionizing radiation. Therefore, it can be an important asset for diagnostic imaging and radiotherapy, enabling better diagnostic outcome with lower radiation dose as well as more versatile characterization of the radiation beam, leading for example to more accurate patient dosimetry. We present our approach of fabricating direct-conversion detectors based on cadmium telluride (CdTe) semiconductor material hybridized with PC mode capable application-specific integrated circuits (ASICs), and will give a review on our achievements, challenges and lessons learned. The CdTe crystals were processed at Micronova, Finland's national research infrastructure for micro- and nanotechnology, employing techniques such as surface passivation via atomic layer deposition, and flip chip bonding of processed sensors to ASIC. Although CdTe has excellent photon radiation absorption properties, it is a brittle material that can include large concentrations of defects. We will therefore also emphasize our quality assessment of CdTe crystals and processed detectors, and present experimental data obtained with prototype detectors in X-ray and Co-60 beams at a standards laboratory.en
dc.description.versionPeer revieweden
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationKirschenmann, S, Bezak, M, Bharthuar, S, Brücken, E, Emzir, M, Golovleva, M, Gädda, A, Kalliokoski, M, Karadzhinova-Ferrer, A, Karjalainen, A, Koponen, P, Kramarenko, N, Luukka, P, Ott, J, Petrow, H, Siiskonen, T, Särkkä, S, Tikkanen, J, Turpeinen, R & Winkler, A 2022, 'Multispectral photon-counting for medical imaging and beam characterization — A project review', Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 1039, 167043. https://doi.org/10.1016/j.nima.2022.167043en
dc.identifier.doi10.1016/j.nima.2022.167043en_US
dc.identifier.issn0168-9002
dc.identifier.issn1872-9576
dc.identifier.otherPURE UUID: 2f256c96-92a1-44e0-a71d-a5e40c0e4546en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/2f256c96-92a1-44e0-a71d-a5e40c0e4546en_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/85936857/Kirschenmann_etal_Multispectral_photon_counting_for_medical_imaging.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/115716
dc.identifier.urnURN:NBN:fi:aalto-202208104538
dc.language.isoenen
dc.publisherElsevier
dc.relation.fundinginfoThe research conducted and presented here was performed in the framework of the Academy of Finland project, number 314473, Multispectral photon-counting for medical imaging and beam characterization, for which we would like to acknowledge the funding. S. Kirschenmann and S. Bharthuar thank the Magnus Ehrnrooth foundation, Finland for financial support. The measurements were performed at the joint Detector Laboratory of the University of Helsinki and the Helsinki Institute of Physics as well as at the Radiation and Nuclear Safety Authority (STUK) and we would like to thank the staff for their support.
dc.relation.ispartofseriesNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipmenten
dc.relation.ispartofseriesVolume 1039en
dc.rightsopenAccessen
dc.subject.keywordDetection of defectsen_US
dc.subject.keywordMaterials for solid-state detectorsen_US
dc.subject.keywordMedical imagingen_US
dc.subject.keywordPhoton counting detectorsen_US
dc.titleMultispectral photon-counting for medical imaging and beam characterization — A project reviewen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion

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