Do sparse brain activity patterns underlie human cognition?

Accumulating multivariate pattern analysis (MVPA) results from fMRI studies suggest that information is represented in fingerprint patterns of activations and deactivations during perception, emotions, and cognition. We postulate that these fingerprint patterns might reflect neuronal-population level sparse code documented in two-photon calcium imaging studies in animal models, i.e., information represented in specific and reproducible ensembles of a few percent of active neurons amidst widespread inhibition in neural populations. We suggest that such representations constitute a fundamental organizational principle via interacting across multiple levels of brain hierarchy, thus giving rise to perception, emotions, and cognition.

Description

Funding Information: Supported by the Academy of Finland ( 332309 ), National Institutes of Health ( R01DC017991 , R01DC016915 , R01DC016765 ) and by the International Laboratory of Social Neurobiology ICN HSE RF Government grant ag. No. 075-15-2022-1037. Publisher Copyright: © 2022

Keywords

Cognition, Emotions, fMRI, MVPA, Perception, Sparse distributed representations

DOI

10.1016/j.neuroimage.2022.119633

Citation

Jääskeläinen , I P , Glerean , E , Klucharev , V , Shestakova , A & Ahveninen , J 2022 , ' Do sparse brain activity patterns underlie human cognition? ' , NeuroImage , vol. 263 , 119633 , pp. 1-4 . https://doi.org/10.1016/j.neuroimage.2022.119633

Permanent link to this item

https://urn.fi/URN:NBN:fi:aalto-202210196024

Collections

[article-cris] Perustieteiden korkeakoulu / SCI

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