Towards the total synthesis of Calyculin C: preparation of the C-13-C-25 spirocyclic core

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date
2009
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Language
en
Pages
7927-7934
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TETRAHEDRON, Volume 65, issue 38
Abstract
A stereoselective synthesis of the C13–C25 of Calyculin C is described. Key steps involve the coupling of a terminal acetylene with a thiol ester and subsequent spirocyclisation using a double intramolecular hetero-Michael addition.
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Habrant , D , Stewart , A J W & Koskinen , A M P 2009 , ' Towards the total synthesis of Calyculin C: preparation of the C-13-C-25 spirocyclic core ' , Tetrahedron , vol. 65 , no. 38 , pp. 7927-7934 . https://doi.org/10.1016/j.tet.2009.07.070