Towards the total synthesis of Calyculin C: preparation of the C-13-C-25 spirocyclic core

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Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2009

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Language

en

Pages

7927-7934

Series

TETRAHEDRON, Volume 65, issue 38

Abstract

A stereoselective synthesis of the C13–C25 of Calyculin C is described. Key steps involve the coupling of a terminal acetylene with a thiol ester and subsequent spirocyclisation using a double intramolecular hetero-Michael addition.

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Citation

Habrant, D, Stewart, A J W & Koskinen, A M P 2009, ' Towards the total synthesis of Calyculin C: preparation of the C-13-C-25 spirocyclic core ', Tetrahedron, vol. 65, no. 38, pp. 7927-7934 . https://doi.org/10.1016/j.tet.2009.07.070