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Highly Enantioselective Conjugate Addition of Thiols Using Mild Scandium Triflate Catalysis

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

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en

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Journal of Organic Chemistry, Volume 72, issue 14, pp. 5411-5413

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A Sc complex of (4S,5S)-diphenyl PYBOX 1 was found to serve as a catalyst for the asymmetric conjugate addition reactions between various thiols and 3-crotonoyl-2-oxazolidinone, affording the corresponding adducts in good yields and high enantioselectivies (up to 92% ee). A new improved method for making (4S,5S)-diphenyl PYBOX is presented.

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Abe, A, Sauerland, S & Koskinen, A 2007, 'Highly Enantioselective Conjugate Addition of Thiols Using Mild Scandium Triflate Catalysis', Journal of Organic Chemistry, vol. 72, no. 14, pp. 5411-5413. https://doi.org/10.1021/jo070492z

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