Electromyography of the muscle spindle
dc.contributor | Aalto-yliopisto | fi |
dc.contributor | Aalto University | en |
dc.contributor.author | Partanen, Juhani V. | en_US |
dc.contributor.author | Vanhanen, Jukka | en_US |
dc.contributor.author | Liljander, Sara K. | en_US |
dc.contributor.department | Department of Neuroscience and Biomedical Engineering | en |
dc.contributor.organization | University of Helsinki | en_US |
dc.date.accessioned | 2022-03-28T09:40:42Z | |
dc.date.available | 2022-03-28T09:40:42Z | |
dc.date.issued | 2022-03-10 | en_US |
dc.description | Publisher Copyright: © 2022, The Author(s). | |
dc.description.abstract | In needle electromyography, there are two spontaneous waveforms, miniature end plate potentials and “end plate spikes”, appearing usually together. Miniature end plate potentials are local, non-propagating postsynaptic waves, caused by spontaneous exocytosis of acetylcholine in the neuromuscular junction. The prevailing hypothesis states that “end plate spikes” are propagated postsynaptic action potentials of muscle fibers, caused by presynaptic irritation of the motor nerve or nerve terminal. Using several small concentric needle electrodes in parallel with the muscle fibers, most “end plate spikes” are strictly local or propagating for 2–4 mm. At the end plate zone, there are miniature end plate potentials without “end plate spikes”. Local “end plate spikes” are junctional potentials of intrafusal gamma neuromuscular junctions of the nuclear bag fibers, and propagated “end plate spikes” are potentials of nuclear chain muscle fibers of muscle spindles. Miniature end plate potentials without “end plate spikes” at the end plate zone derive from alpha neuromuscular junctions. These findings contrast with the prevailing hypothesis. The history of observations and different hypotheses of the origin of end plate spikes are described. | en |
dc.description.version | Peer reviewed | en |
dc.format.extent | 11 | |
dc.format.extent | 1-11 | |
dc.format.mimetype | application/pdf | en_US |
dc.identifier.citation | Partanen, J V, Vanhanen, J & Liljander, S K 2022, ' Electromyography of the muscle spindle ', Scientific Reports, vol. 12, no. 1, 4220, pp. 1-11 . https://doi.org/10.1038/s41598-022-08239-4 | en |
dc.identifier.doi | 10.1038/s41598-022-08239-4 | en_US |
dc.identifier.issn | 2045-2322 | |
dc.identifier.other | PURE UUID: 437b506d-733d-498d-8e2e-1bc61e1e2a90 | en_US |
dc.identifier.other | PURE ITEMURL: https://research.aalto.fi/en/publications/437b506d-733d-498d-8e2e-1bc61e1e2a90 | en_US |
dc.identifier.other | PURE LINK: http://www.scopus.com/inward/record.url?scp=85126203889&partnerID=8YFLogxK | en_US |
dc.identifier.other | PURE FILEURL: https://research.aalto.fi/files/81121778/Electromyography_of_the_muscle_spindle.pdf | en_US |
dc.identifier.uri | https://aaltodoc.aalto.fi/handle/123456789/113751 | |
dc.identifier.urn | URN:NBN:fi:aalto-202203282628 | |
dc.language.iso | en | en |
dc.publisher | Nature Publishing Group | |
dc.relation.ispartofseries | Scientific Reports | en |
dc.relation.ispartofseries | Volume 12, issue 1 | en |
dc.rights | openAccess | en |
dc.title | Electromyography of the muscle spindle | en |
dc.type | A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä | fi |
dc.type.version | publishedVersion |