Design methods for 3D wireframe DNA nanostructures

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Journal Title
Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Date
2018-03
Major/Subject
Mcode
Degree programme
Language
en
Pages
14
1-14
Series
Natural Computing
Abstract
The field of structural DNA nanotechnology aims at the systematic development of self-assembling nanostructures using DNA as the construction material. Research in this area is progressing rapidly, and the controlled, computer-aided design of increasingly complex structures is becoming feasible. One thread of this endeavour is the design and characterisation of self-assembling 3D nanostructures based on wireframe polyhedral models. This article aims to illustrate some of the key developments in this direction, in sufficient detail so that the reader can achieve a general understanding of the main concepts and approaches. The emphasis is on the design principles rather than experimental methodology, and the role of computer science and computational tools is set forth.
Description
Keywords
3D nanostructures, DNA nanotechnology, DNA origami, Self-assembly, Wireframe models
Other note
Citation
Orponen , P 2018 , ' Design methods for 3D wireframe DNA nanostructures ' , Natural Computing , vol. 17 , no. 1 , pp. 147-160 . https://doi.org/10.1007/s11047-017-9647-9