Scavenging properties of plant-derived natural biomolecule para-coumaric acid in the prevention of oxidative stress-induced diseases
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A2 Katsausartikkeli tieteellisessä aikakauslehdessä
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Date
2021-08
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Language
en
Pages
18
Series
Antioxidants, Volume 10, issue 8
Abstract
Para-coumaric acid (p-CA) is a plant derived secondary metabolite belonging to the phenolic compounds. It is widely distributed in the plant kingdom and found mainly in pizza, vegetables, and cereals. Various in vivo and in vitro studies have revealed its scavenging and antioxidative properties in the reduction of oxidative stress and inflammatory reactions. This evidence-based review focuses on the protective role of p-CA including its therapeutic potential. p-CA and its conjugates possesses various bioactivities such as antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, and anti-melanogenic properties. Due to its potent free radical scavenging activity, it can mitigate the ill effects of various diseases including arthritis, neurological disorders, and cardio-vascular diseases. Recent studies have revealed that p-CA can ameliorate the harmful effects associated with oxidative stress in the reproductive system, also by inhibiting enzymes linked with erectile function.Description
Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Keywords
Anti-cancer, Anti-diabetic, Anti-inflammatory, Anti-melanogenic, Antioxidant, Disease, Oxidative stress, Para-coumaric acid, ROS
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Citation
Roychoudhury, S, Sinha, B, Choudhury, B P, Jha, N K, Palit, P, Kundu, S, Mandal, S C, Kolesarova, A, Yousef, M I, Ruokolainen, J, Slama, P & Kesari, K K 2021, ' Scavenging properties of plant-derived natural biomolecule para-coumaric acid in the prevention of oxidative stress-induced diseases ', Antioxidants, vol. 10, no. 8, 1205 . https://doi.org/10.3390/antiox10081205