Applications of lignin nanoparticles for cancer drug delivery: An update

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openAccess

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Volume Title

A2 Katsausartikkeli tieteellisessä aikakauslehdessä

Date

2022-03-15

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Mcode

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Language

en

Pages

3

Series

Materials Letters, Volume 311

Abstract

Cancer is one of the fast-growing diseases with an increasing trend in mortality rate worldwide. Among the treatment modalities, chemotherapy is regarded as an active therapeutic approach where anti-cancer drugs are used to kill cancer cells or arrest its growth. With the emergence of nanotechnology, nanomedicines are being developed to improve the overall pharmaceutical properties of anti-cancer drugs namely drug stability, solubility and bioavailability. Lignin-based nanomaterials are prepared from naturally available lignin polymers, a constituent of lignocellulosic biomass, showcases non-toxic behavior, biodegradable nature, and excellent absorption capacity and are well suited for biomedical applications. This review presents the recent advances on the emerging applications of lignin-based nanomaterials for cancer therapeutics. More importantly, the functional properties of lignin -nanoparticulate systems in cancer drug delivery was discussed.

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Publisher Copyright: © 2021 Elsevier B.V.

Keywords

Anticancer drug, Drug delivery, Lignin, Nanoparticles

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Citation

Garg, J, Nee Chiu, M, Krishnan, S, Kumar Tripathi, L, Pandit, S, Farasati Far, B, Jha, N K, Kesari, K K, Tripathi, V, Pandey, S & Gupta, P K 2022, ' Applications of lignin nanoparticles for cancer drug delivery: An update ', Materials Letters, vol. 311, 131573 . https://doi.org/10.1016/j.matlet.2021.131573