Nanoswimmers Based on Capped Janus Nanospheres

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorPiskunen, Petteri
dc.contributor.authorHuusela, Martina
dc.contributor.authorLinko, Veikko
dc.contributor.departmentBiohybrid Materials
dc.contributor.departmentDepartment of Bioproducts and Biosystems
dc.contributor.departmentDepartment of Bioproducts and Biosystemsen
dc.date.accessioned2022-08-10T08:27:43Z
dc.date.available2022-08-10T08:27:43Z
dc.date.issued2022-07-01
dc.descriptionPublisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
dc.description.abstractNanoswimmers are synthetic nanoscale objects that convert the available surrounding free energy to a directed motion. For example, bacteria with various flagella types serve as textbook examples of the minuscule swimmers found in nature. Along these lines, a plethora of artificial hybrid and non-hybrid nanoswimmers have been introduced, and they could find many uses, e.g., for targeted drug delivery systems (TDDSs) and controlled drug treatments. Here, we discuss a certain class of nanoparticles, i.e., functional, capped Janus nanospheres that can be employed as nanoswimmers, their subclasses and properties, as well as their various implementations. A brief outlook is given on different fabrication and synthesis methods, as well as on the diverse compositions used to prepare nanoswimmers, with a focus on the particle types and materials suitable for biomedical applications. Several recent studies have shown remarkable success in achieving temporally and spatially controlled drug delivery in vitro using Janus-particle-based TDDSs. We believe that this review will serve as a concise introductory synopsis for the interested readers. Therefore, we hope that it will deepen the general understanding of nanoparticle behavior in biological matrices.en
dc.description.versionPeer revieweden
dc.format.mimetypeapplication/pdf
dc.identifier.citationPiskunen , P , Huusela , M & Linko , V 2022 , ' Nanoswimmers Based on Capped Janus Nanospheres ' , Materials , vol. 15 , no. 13 , 4442 . https://doi.org/10.3390/ma15134442en
dc.identifier.doi10.3390/ma15134442
dc.identifier.issn1996-1944
dc.identifier.otherPURE UUID: e012c5c1-b954-44f9-8b19-006375fa8391
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/e012c5c1-b954-44f9-8b19-006375fa8391
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85133258283&partnerID=8YFLogxK
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/85850713/CHEM_Piskunen_et_al_Nanoswimmers_Based_on_Capped_2022_Materials.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/115953
dc.identifier.urnURN:NBN:fi:aalto-202208104775
dc.language.isoenen
dc.publisherMDPI AG
dc.relation.ispartofseriesMaterialsen
dc.relation.ispartofseriesVolume 15, issue 13en
dc.rightsopenAccessen
dc.subject.keywordbiohybrids
dc.subject.keywordbiomedicine
dc.subject.keywordJanus particles
dc.subject.keywordnanofabrication
dc.subject.keywordnanospheres
dc.subject.keywordnanoswimmers
dc.subject.keywordtargeted delivery
dc.titleNanoswimmers Based on Capped Janus Nanospheresen
dc.typeA2 Katsausartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion

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