A short and efficient synthesis of (2S,3S,4S)-tert-butyl 3,4-dihydroxy-2-(methoxymethyl)-5-oxopyrrolidine-1-carboxylate

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openAccess

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Journal Title

Journal ISSN

Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2010

Major/Subject

Mcode

Degree programme

Language

en

Pages

2816-2822

Series

SYNTHESIS: STUTTGART, issue 16

Abstract

Asymmetric synthesis of the title compound was accomplished starting from L-serine. Stannoxane-mediated lactamization provided the key intermediate in good yield.

Description

Keywords

natural products, stereoselective synthesis, olefination, alpha,beta-unsaturated lactam, dihydroxylation

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Citation

Passiniemi , M & Koskinen , A M P 2010 , ' A short and efficient synthesis of (2S,3S,4S)-tert-butyl 3,4-dihydroxy-2-(methoxymethyl)-5-oxopyrrolidine-1-carboxylate ' , SYNTHESIS: STUTTGART , no. 16 , pp. 2816-2822 . https://doi.org/10.1055/s-0029-1218843