Operationalization of Utilitarian and Egalitarian Objectives for Optimal Allocation of Healthcare Resources

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorHynninen, Yrjänäen_US
dc.contributor.authorVilkkumaa, Eevaen_US
dc.contributor.authorSalo, Ahtien_US
dc.contributor.departmentDepartment of Mathematics and Systems Analysisen
dc.contributor.departmentDepartment of Information and Service Managementen
dc.contributor.groupauthorOperations Research and Systems Analysisen
dc.date.accessioned2022-02-02T07:52:34Z
dc.date.available2022-02-02T07:52:34Z
dc.date.issued2021-10en_US
dc.description.abstractResources for health care interventions, such as tests and treatments, are limited. This makes it necessary to prioritize patient segments (defined in terms of their risk) by allocating resources so that the expected contribution to the chosen population-level objective is maximized. In this article, we build a model for the optimal allocation of resources in view of two such objectives: maximizing the aggregate health of the population (utilitarian) and limiting differences in the health outcomes for different patient segments (egalitarian). In particular, we build a two-phase optimization model that (i) first uses dynamic programming to determine what testing and treatment strategies maximize the expected health benefits for each patient segment at different cost levels, and (ii) then solves a binary linear programming problem to determine what resources should be given to each segment to maximize the chosen policy-level objective subject to the overall resource constraint. Our model supports the specification of patient segments, the development of optimal testing and treatment strategies within each segment, and the allocation of available resources to these segments so that the policy-objective will be maximized by implementing these strategies. In addition, the model can be used to guide the interpretation of test results and to assess the impacts of new tests and treatments. It also offers insights into the cost of equity by permitting comparisons between the optimal strategies under utilitarian and egalitarian objectives. We illustrate our approach with real data by optimizing the use of traditional risk scores and genetic tests in preventing coronary heart disease events.en
dc.description.versionPeer revieweden
dc.format.extent40
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationHynninen, Y, Vilkkumaa, E & Salo, A 2021, 'Operationalization of Utilitarian and Egalitarian Objectives for Optimal Allocation of Healthcare Resources', Decision Sciences, vol. 52, no. 5, pp. 1169-1208. https://doi.org/10.1111/deci.12448en
dc.identifier.doi10.1111/deci.12448en_US
dc.identifier.issn0011-7315
dc.identifier.issn1540-5915
dc.identifier.otherPURE UUID: eb92a861-3828-46f2-be60-0b8d6467e3a4en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/eb92a861-3828-46f2-be60-0b8d6467e3a4en_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/78701179/Decision_Sciences_2020_Hynninen_Operationalization_of_Utilitarian_and_Egalitarian_Objectives_for_Optimal_Allocation.pdf
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/112797
dc.identifier.urnURN:NBN:fi:aalto-202202021694
dc.language.isoenen
dc.publisherWiley
dc.relation.ispartofseriesDecision Sciencesen
dc.relation.ispartofseriesVolume 52, issue 5, pp. 1169-1208en
dc.rightsopenAccessen
dc.subject.keywordcoronary heart disease preventionen_US
dc.subject.keywordhealth equityen_US
dc.subject.keywordOR in health servicesen_US
dc.subject.keywordmedical decision makingen_US
dc.subject.keywordmulti-objective optimizationen_US
dc.subject.keywordresource allocationen_US
dc.titleOperationalization of Utilitarian and Egalitarian Objectives for Optimal Allocation of Healthcare Resourcesen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion

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