Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic

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Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2016-07-06

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Mcode

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Language

en

Pages

6
11568-11573

Series

CHEMISTRY: A EUROPEAN JOURNAL, Volume 22, issue 33

Abstract

The catalytic networks of methylotrophic organisms, featuring redox enzymes for the activation of one-carbon moieties, can serve as great inspiration in the development of novel homogeneously catalyzed pathways for the interconversion of C1 molecules at ambient conditions. An imidazolium-tagged arene–ruthenium complex was identified as an effective functional mimic of the bacterial formaldehyde dismutase, which provides a new and highly selective route for the conversion of formaldehyde to methanol in absence of any external reducing agents. Moreover, secondary amines are reductively methylated by the organometallic dismutase mimic in a redox self-sufficient manner with formaldehyde acting both as carbon source and reducing agent.

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Keywords

biocatalysis, ionic liquid, methanol, reductive methylation, Ruthenium

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Citation

van der Waals, D, Heim, L E, Vallazza, S, Gedig, C, Deska, J & Prechtl, M H G 2016, ' Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic ', CHEMISTRY: A EUROPEAN JOURNAL, vol. 22, no. 33, pp. 11568-11573 . https://doi.org/10.1002/chem.201602679