Divergent Mechanistic Scenarios for the C−sp2 and C−sp3 C−H Insertion of Aurated Aryl Cations

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Journal Title

Journal ISSN

Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2023-10-13

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Mcode

Degree programme

Language

en

Pages

8
3320-3327

Series

Advanced Synthesis and Catalysis, Volume 365, issue 19

Abstract

By employing the sterically highly demanding steering ligand IPr* at a gold(I) center, it is possible to induce a 6-endo-dig cyclization pathway in 1,5-diynes bearing terminal alkyne moieties. The resulting aurated naphthyl cations are utilized for the intermolecular formation of C−C bonds via C−H insertion of aromatic and aliphatic C−H bonds. The mechanisms of these transformations were studied by quantum chemical calculations.

Description

Funding Information: J. Bucher is grateful for a Chemiefonds scholarship of the Fonds der Chemischen Industrie. The authors thank Umicore AG & Co. KG for the generous donation of gold salts. Publisher Copyright: © 2023 The Authors. Advanced Synthesis & Catalysis published by Wiley-VCH GmbH.

Keywords

aryl cations, C−H insertion, diynes, gold catalysis, high energy intermediates

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Citation

Bucher, J, Wurm, T, Farshadfar, K, Schukin, M, Uzunidis, G, Rudolph, M, Rominger, F, Ariafard, A & Hashmi, A S K 2023, ' Divergent Mechanistic Scenarios for the C− sp 2 and C− sp 3 C−H Insertion of Aurated Aryl Cations ', Advanced Synthesis and Catalysis, vol. 365, no. 19, pp. 3320-3327 . https://doi.org/10.1002/adsc.202300548