Enantioselective synthesis of a hindered furyl substituted allyl alcohol intermediate: a case study in asymmetric synthesis
| dc.contributor | Aalto-yliopisto | fi |
| dc.contributor | Aalto University | en |
| dc.contributor.author | Pihko, Ainoliisa J. | en_US |
| dc.contributor.author | Lundell, Katri | en_US |
| dc.contributor.author | Kanerva, Liisa | en_US |
| dc.contributor.author | Koskinen, Ari M.P. | en_US |
| dc.contributor.department | Department of Chemistry | en |
| dc.date.accessioned | 2016-09-23T08:17:16Z | |
| dc.date.issued | 2004 | en_US |
| dc.description.abstract | In the course of the synthesis of the DEFG ring system of cneorin C 1, we were faced with the task of preparing the furyl substituted allyl alcohol 5 enantioselectively. Several different methods starting from enantioselective zinc-mediated alkylations were attempted, but none of them proved entirely satisfactory. The solution turned out to be enzymatic kinetic resolution through a highly enantioselective (E > 300) acylation in the presence of Candida antarctica lipase A. | en |
| dc.description.version | Peer reviewed | en |
| dc.format.extent | 1637-1643 | |
| dc.format.mimetype | application/pdf | en_US |
| dc.identifier.citation | Pihko, A J, Lundell, K, Kanerva, L & Koskinen, A M P 2004, ' Enantioselective synthesis of a hindered furyl substituted allyl alcohol intermediate: a case study in asymmetric synthesis ', TETRAHEDRON-ASYMMETRY, no. 15, pp. 1637-1643 . https://doi.org//10.1016/j.tetasy.2004.04.004 | en |
| dc.identifier.doi | /10.1016/j.tetasy.2004.04.004 | en_US |
| dc.identifier.issn | 0957-4166 | |
| dc.identifier.other | PURE UUID: 945457e5-3b6b-455b-b726-6468b8db1c02 | en_US |
| dc.identifier.other | PURE ITEMURL: https://research.aalto.fi/en/publications/945457e5-3b6b-455b-b726-6468b8db1c02 | en_US |
| dc.identifier.other | PURE FILEURL: https://research.aalto.fi/files/7157238/1637.pdf | en_US |
| dc.identifier.uri | https://aaltodoc.aalto.fi/handle/123456789/22330 | |
| dc.identifier.urn | URN:NBN:fi:aalto-201609234334 | |
| dc.language.iso | en | en |
| dc.relation.ispartofseries | TETRAHEDRON-ASYMMETRY | en |
| dc.relation.ispartofseries | issue 15 | en |
| dc.rights | openAccess | en |
| dc.title | Enantioselective synthesis of a hindered furyl substituted allyl alcohol intermediate: a case study in asymmetric synthesis | en |
| dc.type | A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä | fi |
| dc.type.version | acceptedVersion |