Fast Aldol-Tishchenko Reactions Utilizing 1,3-Diol Monoalcoholates as the Catalysts

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date

2001

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Department of Chemistry

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Language

en

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Organic Process Research and Development, Volume 5, issue 4, pp. 421-425

Abstract

The aldol-Tishchenko reaction of enolizable aldehydes is a simple and effective way to prepare 1,3-diol monoesters, which are widely used as coalescing agents in the paint industry. The use of monoalcoholates of 1,3-diols as catalysts gives fast and clean reactions compared with the previous use of several inorganic catalysts. The use of the proper 1,3-diol moiety in the catalyst also reduces the amount of side products which are due to ester interchange between product esters and the catalyst. The rapid water-free method developed herein allows fast preparation of monoesters with excellent yield and minimized formation of side products.

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Keywords

alcoholate, aldol reaction, Aldol-Tishchenko reaction, catalysis, esterification, hydride shift

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DOI

10.1021/op0001335

Citation

Törmäkangas, O P & Koskinen, A M P 2001, 'Fast Aldol-Tishchenko Reactions Utilizing 1,3-Diol Monoalcoholates as the Catalysts', Organic Process Research and Development, vol. 5, no. 4, pp. 421-425. https://doi.org/10.1021/op0001335

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https://urn.fi/URN:NBN:fi:aalto-201609234495

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[article-cris] Kemian tekniikan korkeakoulu / CHEM