Bioactive 3D-Shaped Wound Dressings Synthesized from Bacterial Cellulose: Effect on Cell Adhesion of Polyvinyl Alcohol Integrated In Situ

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© 2017 Marlon Osorio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date

2017

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Department of Bioproducts and Biosystems

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Language

en

Pages

10

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International Journal of Polymer Science, Volume 2017

Abstract

We investigated wound dressing composites comprising fibrils of bacterial cellulose (BC) grown by fermentation in the presence of polyvinyl alcohol (PVA) followed by physical crosslinking. The reference biointerface, neat BC, favoured adhesion of fibroblasts owing to size exclusion effects. Furthermore, it resisted migration across the biomaterial. Such effects were minimized in the case of PVA/BC membranes. Therefore, the latter are suggested in cases where cell adhesion is to be avoided, for instance, in the design of interactive wound dressings with facile exudate control. The bioactivity and other properties of the membranes were related to their morphology and structure and considered those of collagen fibres. Bioactive materials were produced by simple 3D templating of BC during growth and proposed for burn and skin ulcer treatment.

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DOI

10.1155/2017/3728485

Citation

Osorio, M, Velásquez-Cock, J, Restrepo, L M, Zuluaga, R, Gañán, P, Rojas, O J, Ortiz-Trujillo, I & Castro, C 2017, ' Bioactive 3D-Shaped Wound Dressings Synthesized from Bacterial Cellulose : Effect on Cell Adhesion of Polyvinyl Alcohol Integrated In Situ ', International Journal of Polymer Science, vol. 2017, 3728485 . https://doi.org/10.1155/2017/3728485

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https://urn.fi/URN:NBN:fi:aalto-201802091507

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[article-cris] Kemian tekniikan korkeakoulu / CHEM