Auditory representation of learned sound sequences in motor regions of the macaque brain

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Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2020-06-30

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Mcode

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Language

en

Pages

11

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Proceedings of the National Academy of Sciences of the United States of America, Volume 117, issue 26, pp. 15242-15252

Abstract

Human speech production requires the ability to couple motor actions with their auditory consequences. Nonhuman primates might not have speech because they lack this ability. To address this question, we trained macaques to perform an auditory-motor task producing sound sequences via hand presses on a newly designed device ("monkey piano"). Catch trials were interspersed to ascertain the monkeys were listening to the sounds they produced. Functional MRI was then used to map brain activity while the animals listened attentively to the sound sequences they had learned to produce and to two control sequences, which were either completely unfamiliar or familiar through passive exposure only. All sounds activated auditory midbrain and cortex, but listening to the sequences that were learned by self-production additionally activated the putamen and the hand and arm regions of motor cortex. These results indicate that, in principle, monkeys are capable of forming internal models linking sound perception and production in motor regions of the brain, so this ability is not special to speech in humans. However, the coupling of sounds and actions in nonhuman primates (and the availability of an internal model supporting it) seems not to extend to the upper vocal tract, that is, the supralaryngeal articulators, which are key for the production of speech sounds in humans. The origin of speech may have required the evolution of a "command apparatus" similar to the control of the hand, which was crucial for the evolution of tool use.

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Keywords

auditory cortex, internal models, motor cortex, putamen

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Citation

Archakov, D, DeWitt, I, Kuśmierek, P, Ortiz-Rios, M, Cameron, D, Cui, D, Morin, E L, VanMeter, J W, Sams, M, Jääskeläinen, I P & Rauschecker, J P 2020, ' Auditory representation of learned sound sequences in motor regions of the macaque brain ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 26, pp. 15242-15252 . https://doi.org/10.1073/pnas.1915610117