Hemodynamic responses to emotional speech in two-month-old infants imaged using diffuse optical tomography

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorShekhar, Shashanken_US
dc.contributor.authorMaria, Ambikaen_US
dc.contributor.authorKotilahti, Kalleen_US
dc.contributor.authorHuotilainen, Minnaen_US
dc.contributor.authorHeiskala, Juhaen_US
dc.contributor.authorTuulari, Jetro J.en_US
dc.contributor.authorHirvi, Pauliinaen_US
dc.contributor.authorKarlsson, Linneaen_US
dc.contributor.authorKarlsson, Hasseen_US
dc.contributor.authorNissilä, Ilkkaen_US
dc.contributor.departmentDepartment of Neuroscience and Biomedical Engineeringen
dc.contributor.organizationUniversity of Turkuen_US
dc.contributor.organizationUniversity of Helsinkien_US
dc.contributor.organizationDepartment of Neuroscience and Biomedical Engineeringen_US
dc.date.accessioned2019-05-06T09:28:45Z
dc.date.available2019-05-06T09:28:45Z
dc.date.issued2019-12-01en_US
dc.description.abstractEmotional speech is one of the principal forms of social communication in humans. In this study, we investigated neural processing of emotional speech (happy, angry, sad and neutral) in the left hemisphere of 21 two-month-old infants using diffuse optical tomography. Reconstructed total hemoglobin (HbT) images were analysed using adaptive voxel-based clustering and region-of-interest (ROI) analysis. We found a distributed happy > neutral response within the temporo-parietal cortex, peaking in the anterior temporal cortex; a negative HbT response to emotional speech (the average of the emotional speech conditions < baseline) in the temporo-parietal cortex, neutral > angry in the anterior superior temporal sulcus (STS), happy > angry in the superior temporal gyrus and posterior superior temporal sulcus, angry < baseline in the insula, superior temporal sulcus and superior temporal gyrus and happy < baseline in the anterior insula. These results suggest that left STS is more sensitive to happy speech as compared to angry speech, indicating that it might play an important role in processing positive emotions in two-month-old infants. Furthermore, happy speech (relative to neutral) seems to elicit more activation in the temporo-parietal cortex, thereby suggesting enhanced sensitivity of temporo-parietal cortex to positive emotional stimuli at this stage of infant development.en
dc.description.versionPeer revieweden
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationShekhar, S, Maria, A, Kotilahti, K, Huotilainen, M, Heiskala, J, Tuulari, J J, Hirvi, P, Karlsson, L, Karlsson, H & Nissilä, I 2019, 'Hemodynamic responses to emotional speech in two-month-old infants imaged using diffuse optical tomography', Scientific Reports, vol. 9, no. 1, 4745, pp. 1-15. https://doi.org/10.1038/s41598-019-39993-7en
dc.identifier.doi10.1038/s41598-019-39993-7en_US
dc.identifier.issn2045-2322
dc.identifier.otherPURE UUID: fea5635c-0c51-4dd6-925f-d70654da2d5cen_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/fea5635c-0c51-4dd6-925f-d70654da2d5cen_US
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85063327934&partnerID=8YFLogxK
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/32886118/s41598_019_39993_7.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/37813
dc.identifier.urnURN:NBN:fi:aalto-201905062930
dc.language.isoenen
dc.publisherNature Publishing Group
dc.relation.ispartofseriesScientific Reportsen
dc.relation.ispartofseriesVolume 9, issue 1, pp. 1-15en
dc.rightsopenAccessen
dc.titleHemodynamic responses to emotional speech in two-month-old infants imaged using diffuse optical tomographyen
dc.typeA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion

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