Needle bevel geometry influences the flexural deflection magnitude in ultrasound-enhanced fine-needle biopsy

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

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2022-10-12

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en

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Scientific Reports, Volume 12, issue 1

Abstract

It has been recently demonstrated that use of ultrasound increases the tissue yield in ultrasound-enhanced fine-needle aspiration biopsy (USeFNAB) as compared to conventional fine-needle aspiration biopsy (FNAB). To date, the association between bevel geometry and needle tip action has not been widely explored. In this study, we studied the needle resonance characteristics and deflection magnitude of various needle bevel geometries with varying bevel lengths. With a conventional lancet, having a 3.9 mm long bevel, the tip deflection-to-power ratio (DPR) in air and water was 220 and 105 µm/W, respectively. This was higher in comparison to an axi-symmetric tip, having a bevel length of 4 mm, which achieved a DPR of 180 and 80 µm/W in air and water, respectively. This study emphasised the importance of relationship between flexural stiffness of bevel geometry in the context of various insertion media and, thus, could provide understanding on approaches to control post-puncture cutting action by modifying the needle bevel geometry, essential for the USeFNAB application.

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Funding Information: Business Finland (grant 5607/31/2018), the Academy of Finland (grants 311586, 314286, and 335799), and the Finnish Cultural Foundation (personal grant 00210248) are acknowledged for financial support. The authors would like to give thanks to Yohann Le Bourlout and Dr. Gösta Ehnholm for fabrication and design of needle constructs, RF amplifier, and SWR meter. We are grateful to Dr. Maxime Fauconnier for his valuable comments, and we would like to thank all members of the Medical Ultrasonics Laboratory (MEDUSA) at Aalto University (Finland), for the insightful discussions. In addition, the authors would like to thank senior lecturer Kari Santaoja (Aalto University) for the constructive discussions.

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Citation

Bunni, S & Nieminen, H J 2022, ' Needle bevel geometry influences the flexural deflection magnitude in ultrasound-enhanced fine-needle biopsy ', Scientific Reports, vol. 12, no. 1, 17096 . https://doi.org/10.1038/s41598-022-20161-3