Driven polymer translocation into a channel: Isoflux tension propagation theory and Langevin dynamics simulations
Loading...
Access rights
openAccess
publishedVersion
URL
Journal Title
Journal ISSN
Volume Title
A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
This publication is imported from Aalto University research portal.
View publication in the Research portal (opens in new window)
View/Open full text file from the Research portal (opens in new window)
View publication in the Research portal (opens in new window)
View/Open full text file from the Research portal (opens in new window)
Date
Department
Major/Subject
Mcode
Degree programme
Language
en
Pages
14
Series
Physical Review Research, Volume 4, issue 3, pp. 1-14
Abstract
Isoflux tension propagation (IFTP) theory and Langevin dynamics (LD) simulations are employed to study the dynamics of channel-driven polymer translocation in which a polymer translocates into a narrow channel and the monomers in the channel experience a driving force fc. In the high driving force limit, regardless of the channel width, IFTP theory predicts τ∝fcβ for the translocation time, where β=-1 is the force scaling exponent. Moreover, LD data show that for a very narrow channel fitting only a single file of monomers, the entropic force due to the subchain inside the channel does not play a significant role in the translocation dynamics and the force exponent β=-1 regardless of the force magnitude. As the channel width increases the number of possible spatial configurations of the subchain inside the channel becomes significant and the resulting entropic force causes the force exponent to drop below unity.Description
Funding Information: Computational resources from the Center for Scientific Computing Ltd. and from the Aalto University School of Science Science-IT project are gratefully acknowledged. T.A-N. was supported in part by the Academy of Finland through its PolyDyna (Grant No. 307806) and QFT Center of Excellence Program grants (Grant No. 312298). R.M. acknowledges the German Research Foundation (Grant No. ME 1535/12-1) and the Foundation for Polish Science (Humboldt Polish Honorary Research Scholarship) for support. Publisher Copyright: © 2022 authors. Published by the American Physical Society.
Keywords
Other note
Citation
Sarabadani, J, Metzler, R & Ala-Nissila, T 2022, 'Driven polymer translocation into a channel: Isoflux tension propagation theory and Langevin dynamics simulations', Physical Review Research, vol. 4, no. 3, 033003, pp. 1-14. https://doi.org/10.1103/PhysRevResearch.4.033003