Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine

dc.contributorAalto-yliopistofi
dc.contributorAalto Universityen
dc.contributor.authorFerreira, Filipe V.en_US
dc.contributor.authorSouza, Alana G.en_US
dc.contributor.authorAjdary, Rubinaen_US
dc.contributor.authorde Souza, Lucas P.en_US
dc.contributor.authorLopes, João H.en_US
dc.contributor.authorCorrea, Daniel S.en_US
dc.contributor.authorSiqueira, Gilbertoen_US
dc.contributor.authorBarud, Hernane S.en_US
dc.contributor.authorRosa, Derval dos S.en_US
dc.contributor.authorMattoso, Luiz H.C.en_US
dc.contributor.authorRojas, Orlando J.en_US
dc.contributor.departmentDepartment of Bioproducts and Biosystemsen
dc.contributor.groupauthorBio-based Colloids and Materialsen
dc.contributor.organizationNanotechnology National Laboratory for Agricultureen_US
dc.contributor.organizationUniversidade Federal do ABCen_US
dc.contributor.organizationAston Universityen_US
dc.contributor.organizationTechnological Institute of Aeronauticsen_US
dc.contributor.organizationSwiss Federal Laboratories for Materials Science and Technologyen_US
dc.contributor.organizationUniversity of Araraquaraen_US
dc.date.accessioned2023-08-30T04:22:26Z
dc.date.available2023-08-30T04:22:26Z
dc.date.issued2023-11en_US
dc.description| openaire: EC/H2020/788489/EU//BioELCell Funding Information: The authors acknowledge the financial support from the São Paulo Research Foundation [FAPESP; Grants No. 2016/10636-8 , 2020/07956-6 , 2018/22214-6 , 2022/03247-6 ], the Brazilian National Council for Scientific and Technological Development [CNPq; ; Grants No 001 ], the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program [ERC Advanced Grant Agreement No. 788489 , “BioElCell”], the Canada Excellence Research Chair Program [ CERC-2018-00006 ], and Canada Foundation for Innovation [Project number 38623 ]. Publisher Copyright: © 2023 The Authors
dc.description.abstractWe review the recent progress that have led to the development of porous materials based on cellulose nanostructures found in plants and other resources. In light of the properties that emerge from the chemistry, shape and structural control, we discuss some of the most promising uses of a plant-based material, nanocellulose, in regenerative medicine. Following a brief discussion about the fundamental aspects of self-assembly of nanocellulose precursors, we review the key strategies needed for material synthesis and to adjust the architecture of the materials (using three-dimensional printing, freeze-casted porous materials, and electrospinning) according to their uses in tissue engineering, artificial organs, controlled drug delivery and wound healing systems, among others. For this purpose, we map the structure–property–function relationships of nanocellulose-based porous materials and examine the course of actions that are required to translate innovation from the laboratory to industry. Such efforts require attention to regulatory aspects and market pull. Finally, the key challenges and opportunities in this nascent field are critically reviewed.en
dc.description.versionPeer revieweden
dc.format.extent26
dc.format.extent151-176
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationFerreira, F V, Souza, A G, Ajdary, R, de Souza, L P, Lopes, J H, Correa, D S, Siqueira, G, Barud, H S, Rosa, D D S, Mattoso, L H C & Rojas, O J 2023, ' Nanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicine ', Bioactive Materials, vol. 29, pp. 151-176 . https://doi.org/10.1016/j.bioactmat.2023.06.020en
dc.identifier.doi10.1016/j.bioactmat.2023.06.020en_US
dc.identifier.issn2452-199X
dc.identifier.otherPURE UUID: e82b96ec-eec2-4379-b980-aca3285b6eb1en_US
dc.identifier.otherPURE ITEMURL: https://research.aalto.fi/en/publications/e82b96ec-eec2-4379-b980-aca3285b6eb1en_US
dc.identifier.otherPURE LINK: http://www.scopus.com/inward/record.url?scp=85165112235&partnerID=8YFLogxKen_US
dc.identifier.otherPURE FILEURL: https://research.aalto.fi/files/119684922/CHEM_Ferreira_et_al_Nanocellulose_based_porous_2023_Bioactive_Materials.pdfen_US
dc.identifier.urihttps://aaltodoc.aalto.fi/handle/123456789/123009
dc.identifier.urnURN:NBN:fi:aalto-202308305349
dc.language.isoenen
dc.publisherKeAi Communications Co.
dc.relationinfo:eu-repo/grantAgreement/EC/H2020/788489/EU//BioELCell Funding Information: The authors acknowledge the financial support from the São Paulo Research Foundation [FAPESP; Grants No. 2016/10636-8 , 2020/07956-6 , 2018/22214-6 , 2022/03247-6 ], the Brazilian National Council for Scientific and Technological Development [CNPq; ; Grants No 001 ], the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program [ERC Advanced Grant Agreement No. 788489 , “BioElCell”], the Canada Excellence Research Chair Program [ CERC-2018-00006 ], and Canada Foundation for Innovation [Project number 38623 ]. Publisher Copyright: © 2023 The Authorsen_US
dc.relation.ispartofseriesBioactive Materialsen
dc.relation.ispartofseriesVolume 29en
dc.rightsopenAccessen
dc.subject.keywordBiomaterialen_US
dc.subject.keywordCellulose nanocrystalsen_US
dc.subject.keywordCellulose nanofibrilsen_US
dc.subject.keywordGreen nanomaterialsen_US
dc.subject.keywordRegenerative medicineen_US
dc.subject.keywordSustainable materialsen_US
dc.titleNanocellulose-based porous materials: Regulation and pathway to commercialization in regenerative medicineen
dc.typeA2 Katsausartikkeli tieteellisessä aikakauslehdessäfi
dc.type.versionpublishedVersion
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