Lipase-Induced Oxidative Furan Rearrangements

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Journal Title

Journal ISSN

Volume Title

A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Date

2018-01-15

Major/Subject

Mcode

Degree programme

Language

en

Pages

4
1293-1296

Series

Synlett, Volume 29, issue 10

Abstract

Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of N-protected furfurylamines.

Description

Keywords

Achmatowicz, furan, heterocyclic chemistry, pyranone, ring expansion, synthetic methodology

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Citation

Blume, F, Sprengart, P & Deska, J 2018, ' Lipase-Induced Oxidative Furan Rearrangements ', Synlett, vol. 29, no. 10, pp. 1293-1296 . https://doi.org/10.1055/s-0036-1591889