Lipase-Induced Oxidative Furan Rearrangements

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A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
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Date

2018-01-15

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Department of Chemistry and Materials Science

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Language

en

Pages

4

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Synlett, Volume 29, issue 10, pp. 1293-1296

Abstract

Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of N-protected furfurylamines.

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Keywords

Achmatowicz, furan, heterocyclic chemistry, pyranone, ring expansion, synthetic methodology

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DOI

10.1055/s-0036-1591889

Citation

Blume, F, Sprengart, P & Deska, J 2018, 'Lipase-Induced Oxidative Furan Rearrangements', Synlett, vol. 29, no. 10, pp. 1293-1296. https://doi.org/10.1055/s-0036-1591889

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https://urn.fi/URN:NBN:fi:aalto-201812106305

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[article-cris] Kemian tekniikan korkeakoulu / CHEM