Hygiene monitoring biosensing systems in hospital environments

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dc.contributor Aalto-yliopisto fi
dc.contributor Aalto University en
dc.contributor.advisor Anttila, Veli-Jukka; M.D.
dc.contributor.author Köhler, Sebastian
dc.date.accessioned 2011-12-08T09:14:48Z
dc.date.available 2011-12-08T09:14:48Z
dc.date.issued 2006
dc.identifier.uri https://aaltodoc.aalto.fi/handle/123456789/936
dc.description.abstract This thesis concerns the monitoring of biogenic impurities and hygiene in hospital environments by means of biosensing systems. The objective is to find biosensing systems applicable in hospital environments and able to identify pathogens that cause nosocomial infections, on surfaces, in the air and water. In the first part of the thesis, nosocomial infections were investigated, along with their prevalence, mortality, financial aspects and the most common microorganisms causing them. Furthermore. existing national and international nosocomial infection surveillance programmes, as well as organisations and journals associated with this field, were pinned down. Collaboration with the Meilahti Helsinki University Central Hospital enabled examination of their nosocomial infection status and familiarisation with their current prevention practices. The most important is good hand hygiene, trailed by, among others, pressurisation and filtration of air; limited use of tap water; and good overall cleanliness. Products that monitor or test the hygiene level are not in routine use. Three areas, where biosensing systems could be of use in a hospital, were identified. These are the ventilation system, the water distribution system and cleaning. The second part of the thesis discusses biosensing systems. Various methods were mapped in an overview of this field, comprising electrochemical, optical, microelectromechanical, nucleic acid- and cell-based systems. Based on this, the most promising methods – laser- and light-emitting diode-induced fluorescence and biocavity lasing – were explored further. These have the potential to detect microbes eminently fast, even in real time. Use of the fluorescence method to verify the functioning of filters in the ventilation system has been evaluated, as well as the biocavity laser's potential to validate the purity of water and the cleanliness of surfaces in conjunction with cleaning. Rapid biosensing systems based on the aforementioned novel methods are also applicable to, among others, flow cytometry devices used for gene sequencing. en
dc.format.extent 90
dc.format.mimetype application/pdf
dc.language.iso en en
dc.publisher Helsinki University of Technology en
dc.publisher Teknillinen korkeakoulu fi
dc.subject.other Electrical engineering en
dc.subject.other Medical sciences en
dc.title Hygiene monitoring biosensing systems in hospital environments en
dc.type G2 Pro gradu, diplomityö fi
dc.contributor.department Department of Electrical and Communications Engineering en
dc.contributor.department Sähkö- ja tietoliikennetekniikan osasto fi
dc.subject.keyword biosensing systems en
dc.subject.keyword hygiene monitoring en
dc.subject.keyword biosensor en
dc.subject.keyword nosocomial infection en
dc.subject.keyword hospital en
dc.subject.keyword microbe en
dc.subject.keyword detection en
dc.subject.keyword biosensorsystem sv
dc.subject.keyword hygienövervakning sv
dc.subject.keyword biosensor sv
dc.subject.keyword sjukhusinfektion sv
dc.subject.keyword sjukhus sv
dc.subject.keyword mikrob sv
dc.subject.keyword detektion sv
dc.identifier.urn urn:nbn:fi:tkk-007335
dc.type.dcmitype text en
dc.programme.major Laskennallinen tekniikka fi
dc.programme.mcode S-114
dc.type.ontasot Diplomityö fi
dc.type.ontasot Master's thesis en
dc.contributor.supervisor Tulkki, Jukka; Prof.
dc.programme Elektroniikan ja sähkötekniikan koulutusohjelma fi
dc.contributor.lab Laboratory of Computational Engineering en
dc.contributor.lab Laskennallisen tekniikan laboratorio fi
dc.location P1 fi

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