Title: | Data-analysis perspectives on naturalistic stimulation in functional magnetic resonance imaging |
Author(s): | Malinen, Sanna |
Date: | 2010 |
Language: | en |
Pages: | Verkkokirja (1284 KB, 42 s.) |
Department: | Lääketieteellisen tekniikan ja laskennallisen tieteen laitos Department of Biomedical Engineering and Computational Science |
ISBN: | 978-952-60-3208-5 (electronic) 978-952-60-3207-8 (printed) |
Series: | TKK dissertations, 230 |
ISSN: | 1795-4584 |
Supervising professor(s): | Ilmoniemi, Risto, Prof. |
Thesis advisor(s): | Hari, Riitta, Academy Prof. |
Subject: | Medical sciences, Electrical engineering |
Keywords: | functional magnetic resonance imaging, statistical parametric mapping, independent component analysis, correlation analysis, brain |
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Abstract:Modern brain imaging allows to study human brain function during naturalistic stimulus conditions, which entail specific challenges for the analysis of the brain signals. The conventional analysis of data obtained by functional magnetic resonance imaging (fMRI) is based on user-specified models of the temporal behavior of the signals (general linear model, GLM). Alongside these approaches, data-based methods can be applied to model the signal behavior either on the basis of the measured data, as in seed-point correlations or inter-subject correlations (ISC), or alternatively the temporal behavior is not modeled, but spatial signal sources and related time courses are estimated directly from the measured data (independent component analysis, ICA).
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Parts:[Publication 1]: Sanna Malinen, Martin Schürmann, Yevhen Hlushchuk, Nina Forss, and Riitta Hari. 2006. Improved differentiation of tactile activations in human secondary somatosensory cortex and thalamus using cardiac-triggered fMRI. Experimental Brain Research, volume 174, number 2, pages 297-303.[Publication 2]: Sanna Malinen, Yevhen Hlushchuk, and Riitta Hari. 2007. Towards natural stimulation in fMRI—Issues of data analysis. NeuroImage, volume 35, number 1, pages 131-139. © 2006 Elsevier Science. By permission.[Publication 3]: Sanna Malinen and Riitta Hari. 2010. Comprehension of audiovisual speech: Data-based sorting of independent components of fMRI activity. Espoo, Finland: Aalto University School of Science and Technology. 14 pages. Helsinki University of Technology, Low Temperature Laboratory Publications, Report TKK-KYL-023. ISBN 978-952-60-3170-5. © 2010 by authors.[Publication 4]: Sanna Malinen, Nuutti Vartiainen, Yevhen Hlushchuk, Miika Koskinen, Pavan Ramkumar, Nina Forss, Eija Kalso, and Riitta Hari. 2010. Aberrant temporal and spatial brain activity during rest in patients with chronic pain. Proceedings of the National Academy of Sciences of the United States of America, volume 107, number 14, pages 6493-6497. © 2010 by authors. |
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